Resistance to apoptosis is closely linked to tumorigenesis, as it enables malignant cells to
expand even in a stressful environment. Cells resistant to apoptosis are also assumed to be …

Resistance towards apoptosis is a key factor for the survival of a malignant cell. Cancer
results if there is too little apoptosis and cells grow faster and live longer than normal cells. In …

Over the past 10 years evidence has been accumulating that antitumour agents induce
apoptosis in cancer cells and that abnormalities in apoptosis signaling pathways often occur …

Cancer is a multifaceted disease comprising a combination of genetic, metabolic and
signalling aberrations, which severely disrupt the normal homeostasis of cell growth and …

Apoptosis is a cell suicide program that plays a critical role in development and tissue
homeostasis. The ability of cancer cells to evade this programmed cell death (PCD) is a …

Each day, approximately 50 to 70 billion cells perish in the average adult because of
programmed cell death (PCD). Cell death in self-renewing tissues, such as the skin, gut, and …

Killing of tumor cells by anticancer therapies commonly used in the treatment of cancer, eg
chemotherapy, γ-irradiation, immunotherapy or suicide gene therapy, is predominantly …

Apoptosis in human cancer cells : Current Opinion in Oncology Apoptosis in human cancer
cells : Current Opinion in Oncology Log in or Register Subscribe to journalSubscribe Get new …

Apoptosis, the most extensively studied form of programmed cell death, is essential for
organismal homeostasis. Apoptotic cell death has widely been reported as a tumor …

Apoptosis, the cell's intrinsic program to death, plays a central role in physiological growth
control and regulation of tissue homeostasis. Tipping the balance between cell death and …