Multiple sclerosis (MS) is a complex disease with significant heterogeneity in disease course
and progression. Genetic studies have identified numerous loci associated with MS risk, but …

Animal models with high translational validity are essential tools in understanding disease
pathogenesis and in the development of therapeutic strategies. Multiple sclerosis (MS) is an …

Unbiased genetic analysis of experimental autoimmune encephalomyelitis (EAE) can
provide insights into the pathogenesis of multiple sclerosis. To date five genome-wide scans …

Multiple sclerosis is a leading cause of neurological disability in adults. Heterogeneity in
multiple sclerosis clinical presentation has posed a major challenge for identifying genetic …

Using a mouse model of multiple sclerosis (MS), experimental autoimmune encephalitis
(EAE), we evaluated the role of gut microbiota in modulating chronic-progressive (CP) …

INTRODUCTION Multiple sclerosis (MS) is an inflammatory and degenerative disease of the
central nervous system (CNS) that often presents in young adults. Over the past decade …

Limited studies have been conducted to identify and validate multiple sclerosis (MS) genetic
loci associated with disability progression. We aimed to identify MS genetic loci associated …

Background To elucidate mechanisms involved in multiple sclerosis (MS), we studied
genetic regulation of experimental autoimmune encephalomyelitis (EAE) in rats, assuming a …

Experimental autoimmune encephalomyelitis (EAE) remains a widely used pre-clinical
animal model to study multiple sclerosis (MS). Blood-based cytokines and CNS biomarkers …

Background The mechanisms driving multiple sclerosis (MS), the most common cause of
non-traumatic disability in young adults, remain unknown despite extensive research …