Obesity is associated with severe metabolic diseases such as type 2 diabetes, insulin
resistance, cardiovascular disease and some forms of cancer. The pathophysiology of …

Brown adipose tissue (BAT) catabolizes glucose and fatty acids to produce heat and thereby
contributes to energy expenditure. Long-term high-fat diet (HFD) feeding results in so-called …

Obesity results in the chronic activation of innate immune system and subsequently sets in
diabetes. Aim of the study was to investigate the immunometabolic role of brown adipose …

Systemic inflammation resulting from dysfunction of white adipose tissue (WAT) accelerates
the pathologies of diabetes and cardiovascular diseases. In contrast to WAT, brown adipose …

Background High-fat diet (HFD)-induced obesity causes immune cells to infiltrate adipose
tissue, leading to chronic inflammation and metabolic syndrome. Brown adipose tissue …

Obesity leads to various changes in the body. Among them, the existing inflammatory
process may lead to an increase in the production of reactive oxygen species (ROS) and …

Adipose tissue metabolism is a critical regulator of adiposity and whole body energy
expenditure; however, metabolic changes that occur in white adipose tissue (WAT) with …

Pattern recognition receptors (PRR), Toll-like receptors (TLR), and nucleotide-
oligomerization domain-containing proteins (NOD) play critical roles in mediating …

Brown adipose tissue (BAT) dissipates energy to produce heat. Thus, it has the potential to
regulate body temperature by thermogenesis. For the last decade, BAT has been in the …

Overnutrition and sedentary activity reinforce the growing trend of worldwide obesity, insulin
resistance, and type 2 diabetes. However, we have limited insight into how food intake …