Development of new treatments for drug addiction will depend on high-throughput screening
in animal models. However, an addiction biomarker fit for rapid testing, and useful in both …

Background Evidence indicates that oxytocin, an endogenous peptide well known for its role
in social behaviors, childbirth, and lactation, is a promising addiction pharmacotherapy. We …

The intersection of pharmacological, psychological, and economic theory within behavioral
economics has helped advance an understanding of substance use disorder. A notable …

Interest for the use of oxytocin as a treatment for addiction began over 40 years ago. Better
known for its roles in parturition, lactation and pair bonding, oxytocin also has anxiolytic …

Behavioral economics is a powerful, translational approach for measuring drug demand in
both humans and animals. Here, we asked if demand for cocaine in rats with limited drug …

Substance abusers, including cocaine abusers, discount delayed rewards to a greater
extent than do matched controls. In the current experiment, individual differences in …

Oxytocin has been shown to decrease cocaine taking and seeking in male rats, suggesting
potential treatment efficacy for drug addiction. In the present study, we extended these …

Background Assessing the relative value of cocaine and how it changes with chronic drug
use represents a long-standing goal in addiction research. Surprisingly, recent experiments …

Tobacco and alcohol dependence are characterized by continued use despite deleterious
health, social and occupational consequences, implying that addicted individuals pay a high …

Rationale Taking high and increasing amounts of cocaine is thought to be necessary for the
development of addiction. Consequently, a widely used animal model of drug self …