Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances
SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …
sensory, motor and autonomic impairments after SCI are substantially attributed to …
[HTML][HTML] Advances in neural stem cell therapy for spinal cord injury: safety, efficacy, and future perspectives
S Lee, H Nam, KM Joo, SH Lee - Neurospine, 2022 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) is a devastating central nervous system injury that leads to severe
disabilities in motor and sensory functions, causing significant deterioration in patients' …
disabilities in motor and sensory functions, causing significant deterioration in patients' …
Review of transplantation of neural stem/progenitor cells for spinal cord injury
AJ Mothe, CH Tator - International Journal of Developmental Neuroscience, 2013 - Elsevier
Spinal cord injury (SCI) is a debilitating condition often resulting in paralysis, yet currently
there is no effective treatment. Stem cell transplantation is a promising therapeutic strategy …
there is no effective treatment. Stem cell transplantation is a promising therapeutic strategy …
Regenerative replacement of neural cells for treatment of spinal cord injury
WB McIntyre, K Pieczonka, M Khazaei… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: Traumatic Spinal Cord Injury (SCI) results from primary physical
injury to the spinal cord, which initiates a secondary cascade of neural cell death. Current …
injury to the spinal cord, which initiates a secondary cascade of neural cell death. Current …
Improving the therapeutic efficacy of neural progenitor cell transplantation following spinal cord injury
Introduction: There have been a wide range of preclinical studies testing cellular therapies to
repair the injured spinal cord, yet they remain a challenge to translate because of …
repair the injured spinal cord, yet they remain a challenge to translate because of …
[HTML][HTML] Current concepts of neural stem/progenitor cell therapy for chronic spinal cord injury
Chronic spinal cord injury (SCI) is a devastating condition that results in major neurological
deficits and social burden. It continues to be managed symptomatically, and no real …
deficits and social burden. It continues to be managed symptomatically, and no real …
Neural stem cells for spinal cord repair
Spinal cord injury (SCI) causes the irreversible loss of spinal cord parenchyma including
astroglia, oligodendroglia and neurons. In particular, severe injuries can lead to an almost …
astroglia, oligodendroglia and neurons. In particular, severe injuries can lead to an almost …
[HTML][HTML] A narrative review of advances in neural precursor cell transplantation therapies for spinal cord injury
A spinal cord injury (SCI) is a destructive event that causes a permanent deficit in
neurological function because of poor regenerative potential. Transplantation therapies …
neurological function because of poor regenerative potential. Transplantation therapies …
Human spinal oligodendrogenic neural progenitor cells enhance pathophysiological outcomes and functional recovery in a clinically relevant cervical spinal cord …
K Pieczonka, H Nakashima, N Nagoshi… - Stem Cells …, 2023 - academic.oup.com
Traumatic spinal cord injury (SCI) results in the loss of neurons, oligodendrocytes, and
astrocytes. Present interventions for SCI include decompressive surgery, anti-inflammatory …
astrocytes. Present interventions for SCI include decompressive surgery, anti-inflammatory …
The application of neural stem/progenitor cells for regenerative therapy of spinal cord injury
C Yu, K Xia, Z Gong, L Ying, J Shu… - Current stem cell …, 2019 - ingentaconnect.com
Spinal cord injury (SCI) is a devastating event, and there are still no effective therapies
currently available. Neural stem cells (NSCs) have gained increasing attention as promising …
currently available. Neural stem cells (NSCs) have gained increasing attention as promising …