Hydroxyprostaglandin dehydrogenase (HPGD) plays a key role in prostaglandins (PGs)
catabolism. Its expression and activity appear to be regulated by progesterone (P4). We …

Prostaglandins are key components of the parturition cascade; however, the mechanisms
that regulate prostaglandin concentrations in the uterus during pregnancy are largely …

Prostaglandins (PG) are primary regulators of reproductive function. In ruminants, the
relative production of PGE 2 and PGF 2α determines the return to a new oestrous cycle or to …

NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (PGDH) is the key catabolic
enzyme controlling levels of biologically active PGs. PGDH is localized to …

Abstract Type 1 15-hydroxyprostaglandin dehydrogenase (PGDH) is the main enzyme
responsible for the metabolism of prostaglandin E2 (PGE2) and PGF2 alpha. To examine …

Prostaglandins play a central role in the stimulation and maintenance of both term and
preterm labor. 15-Hydroxyprostaglandin dehydrogenase (PGDH), localized primarily to …

The aim of the following study was to test the hypothesis that an increased local catabolism
of prostaglandin F 2α might at least in part be responsible for the lower placental tissue …

Increased prostaglandin production by tissues in the sheep uterus and placenta are thought
to be important for the onset of parturition. In the sheep placenta, this is most likely due to …

The prostaglandin (PG)-inactivating enzyme 15-hydroxyprostaglandin dehydrogenase
(PGDH) is highly expressed in the chorion leave. To assess the involvement of PGDH in the …

Prostaglandin F2α (PGF2α) and PGE2 produced by the uterine tissues have long been
considered to be important during pregnancy for the regulation of blood flow (Carter, 1998) …