Radioligand binding has been used for many years to identify new binding sites,
characterize receptors, and identify novel ligands. Although various techniques have been …

Radioligand binding is an extremely versatile technique that can be applied to a wide range
of receptors in a variety of preparations, including purified and solubilized receptors …

Since a drug acting at a receptor must bind to the receptor before exerting an effect, it may
seem obvious that measuring directly the binding of radio-labeled drugs, alone and in …

Radioligand binding assays are routinely utilized in laboratories throughout the world to
study receptors and their related binding sites, carrier proteins, and enzymes. To accurately …

Radioligand binding is essentially a very simple technique, applicable to a wide range of
preparations. It can of course be used to study many different types of receptors, but can also …

Radioligand binding assays are a relatively simple but extremely powerful tool for studying
receptors. They allow an analysis of the interactions of hormones, neurotransmitters, growth …

The receptor concept was developed to explain the specific effect of a minute amount of
substrate on a target organ. Receptor-binding radiotracers are meant to measure only the …

The development of receptor-targeting radiopharmaceuticals commonly involves the use of
peptides, antibodies or small molecules. Resulting from the numerous modifications that can …

Transmitters and hormones generate signals in target cells by interacting with a signal
transducing protein or receptor. Receptors may be located in the cytosol, allowing for …

The reversible combination of a ligand with specific sites on the surface of a receptor is one
of the most important processes in biochemistry. A classic equation with a useful simple …