Hemodynamic stress and chronic inflammation are closely associated with the pathogenesis
of intracranial aneurysms (IAs). However, the hemodynamic and biological mechanisms …

Aneurysm wall remodeling (AWR) is an important pathological characteristic in aneurysm
wall, which was characterized by abnormal histological structure and inflammation …

Past studies have elucidated the crucial role of macrophage-mediated inflammation in the
growth of intracranial aneurysms (IAs), but the contributions of hemodynamics are unclear …

Intracranial aneurysm (IA) usually induced at a bifurcation site of intracranial arteries causes
a lethal subarachnoid hemorrhage. Currently, IA is considered as a macrophage-mediated …

Intracranial aneurysm (IA) is a socially important disease both because it has a high
prevalence and because of the severity of resultant subarachnoid hemorrhages after IA …

Background There seems to be a pathogenetic link between hemodynamics and
inflammatory arterial wall alteration leading to the development and rupture of intracranial …

BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …

Background: Studying the relationship between hemodynamics and local intracranial
aneurysm (IA) pathobiology can help us understand the natural history of IA. We …

Although fluctuating hemodynamic wall stressors are known to impact intracranial
aneurysms (IA) initiation, specificity of those stressors has not been evaluated. In this study …

Background Intracranial aneurysm (IA) is a disease of the vascular wall resulting in
abnormal enlargement of the vessel lumen. It is a common pathology with a prevalence of …