[HTML][HTML] The combination of multi-approach studies to explore the potential therapeutic mechanisms of imidazole derivatives as an MCF-7 inhibitor in therapeutic …
Breast cancer covers a large area of research because of its prevalence and high frequency
all over the world. This study is based on drug discovery against breast cancer from a series …
all over the world. This study is based on drug discovery against breast cancer from a series …
In silico studies on potential MCF-7 inhibitors: a combination of pharmacophore and 3D-QSAR modeling, virtual screening, molecular docking, and pharmacokinetic …
Gallic acid and its derivatives exhibit a diverse range of biological applications, including
anti-cancer activity. In this work, a data-set of forty-six molecules containing the galloyl …
anti-cancer activity. In this work, a data-set of forty-six molecules containing the galloyl …
[PDF][PDF] Plant derived bioactive compounds, their anti-cancer effects and in silico approaches as an alternative target treatment strategy for breast cancer: An updated …
V Shrihastini, P Muthuramalingam, S Adarshan… - 2021 - researchgate.net
Cancer is one of the most common malignant diseases that occur worldwide, among which
breast cancer is the second leading cause of death in women. The subtypes are associated …
breast cancer is the second leading cause of death in women. The subtypes are associated …
Design, synthesis, and computational validation of novel compounds selectively targeting HER2-expressing breast cancer
Human epidermal growth factor receptor (HER) is a family of multidomain proteins that plays
important role in the regulation of several biological functions. HER2 is a member of HER …
important role in the regulation of several biological functions. HER2 is a member of HER …
Exploring the Potential of Substituted 4-Thiazolidinone Derivatives in the Treatment of Breast Cancer: Synthesis, Biological Screening and In Silico Studies
A series of 4-thiazolidinone conjugates bearing quinoline/indole/furan scaffolds were
designed as potential anti-breast cancer agents, synthesized, and investigated for their anti …
designed as potential anti-breast cancer agents, synthesized, and investigated for their anti …
[HTML][HTML] Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An …
V Shrihastini, P Muthuramalingam, S Adarshan… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is one of the leading causes of death among women
worldwide. Breast cancer may be provoked due to several physical, chemical and …
worldwide. Breast cancer may be provoked due to several physical, chemical and …
[PDF][PDF] Insight on the in silico study and biological activity assay of chalcone-based 1, 5-benzothiazepines as potential inhibitor for breast cancer MCF7. CMUJ
In silico study was performed to twelve 1, 5-benzothiazepine chalcone derivatives with the
protein target from the crystallographic structure modeling of the enzyme tyrosine kinase …
protein target from the crystallographic structure modeling of the enzyme tyrosine kinase …
[HTML][HTML] Screening of phytochemicals as potential inhibitors of breast cancer using structure based multitargeted molecular docking analysis
V Jha, S Devkar, K Gharat, S Kasbe, DK Matharoo… - Phytomedicine …, 2022 - Elsevier
Background: Breast cancer being one of the most common cancers in women all around the
world is a dominant cause of deaths occurring all around the globe. The available potent …
world is a dominant cause of deaths occurring all around the globe. The available potent …
Generating a potent inhibitor against MCF7 breast cancer cell through artificial intelligence based virtual screening and molecular docking studies
Artificial Intelligence (AI) has been widely adopted by pharmaceutical industry to aid
rationally drug design and development by fostering the quick delivery of drug targets with …
rationally drug design and development by fostering the quick delivery of drug targets with …
Predictive hybrid paradigm for cytotoxic activity of 1, 3, 4-thiadiazole derivatives as CDK6 inhibitors against human (MCF-7) breast cancer cell line and its structural …
The dysregulation of cyclin-CDK6 interactions has been implicated in human breast cancer,
providing a rationale for more therapeutic options. Recently, ATP-competitive inhibitors have …
providing a rationale for more therapeutic options. Recently, ATP-competitive inhibitors have …