Integrated biosensor for rapid and point-of-care sepsis diagnosis
Sepsis is an often fatal condition that arises when the immune response to an infection
causes widespread systemic organ injury. A critical unmet need in combating sepsis is the …
causes widespread systemic organ injury. A critical unmet need in combating sepsis is the …
[HTML][HTML] Nanoparticle-based mobile biosensors for the rapid detection of sepsis biomarkers in whole blood
A Alba-Patino, SM Russell, M Borges… - Nanoscale …, 2020 - pubs.rsc.org
Detecting small variations in the levels of IL-6 is crucial for the early diagnosis of sepsis. To
be useful in clinical decision-making, this requires detecting IL-6 rapidly in whole blood and …
be useful in clinical decision-making, this requires detecting IL-6 rapidly in whole blood and …
Multiplexed cytokine detection using electrochemical point-of-care sensing device towards rapid sepsis endotyping
AS Tanak, S Muthukumar, S Krishnan… - Biosensors and …, 2021 - Elsevier
The implementation of endotype-driven effective intervention strategies is now considered
as an essential component for sepsis management. Rapid screening and frequent …
as an essential component for sepsis management. Rapid screening and frequent …
Rapid detection of sepsis: recent advances in biomarker sensing platforms
Sepsis is a major cause of mortality among hospitalized patients worldwide. Rapid
diagnosis is critical as early treatments have been demonstrated to improve survival …
diagnosis is critical as early treatments have been demonstrated to improve survival …
[HTML][HTML] Micro-and nanosensors for detecting blood pathogens and biomarkers at different points of sepsis care
A Alba-Patiño, A Vaquer, E Barón, SM Russell… - Microchimica Acta, 2022 - Springer
Severe infections can cause a dysregulated response leading to organ dysfunction known
as sepsis. Sepsis can be lethal if not identified and treated right away. This requires …
as sepsis. Sepsis can be lethal if not identified and treated right away. This requires …
[HTML][HTML] Development of a needle shaped microelectrode for electrochemical detection of the sepsis biomarker interleukin-6 (IL-6) in real time
C Russell, AC Ward, V Vezza, P Hoskisson… - Biosensors and …, 2019 - Elsevier
This paper outlines a simple label-free sensor system for the sensitive, real time
measurement of an important protein biomarker of sepsis, using a novel microelectrode …
measurement of an important protein biomarker of sepsis, using a novel microelectrode …
Recent advances in biosensors for diagnosis and detection of sepsis: A comprehensive review
Sepsis is one of the leading causes of mortality among critically ill patients globally.
According to WHO report 2018, it is estimated to affect beyond 30 million people worldwide …
According to WHO report 2018, it is estimated to affect beyond 30 million people worldwide …
[HTML][HTML] Advances in sepsis diagnosis and management: a paradigm shift towards nanotechnology
Sepsis, a dysregulated immune response due to life-threatening organ dysfunction, caused
by drug-resistant pathogens, is a major global health threat contributing to high disease …
by drug-resistant pathogens, is a major global health threat contributing to high disease …
Toward the rapid diagnosis of sepsis: detecting interleukin-6 in blood plasma using functionalized screen-printed electrodes with a thermal detection methodology
RD Crapnell, W Jesadabundit… - Analytical …, 2021 - ACS Publications
This paper reports the detection of the inflammatory and sepsis-related biomarker,
interleukin-6 (IL-6), in human blood plasma using functionalized screen-printed electrodes …
interleukin-6 (IL-6), in human blood plasma using functionalized screen-printed electrodes …
[HTML][HTML] Point-of-care diagnostics for sepsis using clinical biomarkers and microfluidic technology
Sepsis is a life-threatening immune response which is caused by a wide variety of sources
and is a leading cause of mortality globally. Rapid diagnosis and appropriate antibiotic …
and is a leading cause of mortality globally. Rapid diagnosis and appropriate antibiotic …