A new frontier in temporomandibular joint osteoarthritis treatment: Exosome-based therapeutic strategy
W Yuan, Y Wu, M Huang, X Zhou, J Liu, Y Yi… - … in Bioengineering and …, 2022 - frontiersin.org
Temporomandibular joint osteoarthritis (TMJOA) is a debilitating degenerative disease with
high incidence, deteriorating quality of patient life. Currently, due to ambiguous etiology, the …
high incidence, deteriorating quality of patient life. Currently, due to ambiguous etiology, the …
Emerging potential of exosomes in regenerative medicine for temporomandibular joint osteoarthritis
Exosomes are nanosized vesicles (30–140 nm) of endocytic origin that play important roles
in regenerative medicine. They are derived from cell membranes during endocytic …
in regenerative medicine. They are derived from cell membranes during endocytic …
MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis
The efficacy of mesenchymal stem cell (MSC) therapies is increasingly attributed to
paracrine secretion, particularly exosomes. In this study, we investigated the role of MSC …
paracrine secretion, particularly exosomes. In this study, we investigated the role of MSC …
Exosomes of stem cells from human exfoliated deciduous teeth as an anti-inflammatory agent in temporomandibular joint chondrocytes via miR-100-5p/mTOR
P Luo, C Jiang, P Ji, M Wang, J Xu - Stem Cell Research & Therapy, 2019 - Springer
Objectives Temporomandibular joint osteoarthritis (TMJOA) is an inflammatory joint disease.
This study investigated whether exosomes (Exos) of stem cells from human exfoliated …
This study investigated whether exosomes (Exos) of stem cells from human exfoliated …
Exosomes derived from MSC as drug system in osteoarthritis therapy
S Wen, X Huang, J Ma, G Zhao, T Ma… - … in Bioengineering and …, 2024 - frontiersin.org
Osteoarthritis (OA) is the most common degenerative disease of the joint with irreversible
cartilage damage as the main pathological feature. With the development of regenerative …
cartilage damage as the main pathological feature. With the development of regenerative …
Research progress in the use of mesenchymal stem cells and their derived exosomes in the treatment of osteoarthritis
H Yu, Y Huang, L Yang - Ageing research reviews, 2022 - Elsevier
Osteoarthritis (OA), as a common orthopedic disease with cartilage injury as its main
pathological feature, has a complex pathogenesis and existing medical technology remains …
pathological feature, has a complex pathogenesis and existing medical technology remains …
Mesenchymal stem cell-derived exosomes as a promising cell-free therapy for knee osteoarthritis
D Luo, H Zhu, S Li, Z Wang, J Xiao - Frontiers in Bioengineering and …, 2024 - frontiersin.org
Osteoarthritis (OA), as a degenerative disease, leads to high socioeconomic burdens and
disability rates. The knee joint is typically the most affected and is characterized by …
disability rates. The knee joint is typically the most affected and is characterized by …
Enhancement of the therapeutic efficacy of mesenchymal stem cell-derived exosomes in osteoarthritis
Z Zhang, S Zhao, Z Sun, C Zhai, J Xia, C Wen… - Cellular & Molecular …, 2023 - Springer
Osteoarthritis (OA), a common joint disorder with articular cartilage degradation as the main
pathological change, is the major source of pain and disability worldwide. Despite current …
pathological change, is the major source of pain and disability worldwide. Despite current …
The role and therapeutic potential of MSC-derived exosomes in osteoarthritis
C Bao, C He - Archives of Biochemistry and Biophysics, 2021 - Elsevier
Osteoarthritis (OA) is the most common painful disease with chronic articular cartilage
degeneration. The pathological process of OA is complex and characterized by the …
degeneration. The pathological process of OA is complex and characterized by the …
Engineering of MSC-derived exosomes: a promising cell-free therapy for osteoarthritis
J Cheng, Y Sun, Y Ma, Y Ao, X Hu, Q Meng - Membranes, 2022 - mdpi.com
Osteoarthritis (OA) is characterized by progressive cartilage degeneration with increasing
prevalence and unsatisfactory treatment efficacy. Exosomes derived from mesenchymal …
prevalence and unsatisfactory treatment efficacy. Exosomes derived from mesenchymal …