Fetal alcohol spectrum disorders: Zebrafish in the analysis of the milder and more prevalent form of the disease

D Seguin, R Gerlai - Behavioural brain research, 2018 - Elsevier
Abstract Fetal Alcohol Spectrum Disorders (FASD) represent a large unmet medical need.
Exposure of the developing human embryo to alcohol can lead to life-long suffering. Despite …

Embryonic alcohol exposure: Towards the development of a zebrafish model of fetal alcohol spectrum disorders

R Gerlai - Developmental Psychobiology, 2015 - Wiley Online Library
Fetal alcohol spectrum disorder (FASD) is a devastating disease of the brain caused by
exposure to alcohol during prenatal development. Its prevalence exceeds 1%. The majority …

Fishing for fetal alcohol spectrum disorders: zebrafish as a model for ethanol teratogenesis

CB Lovely, Y Fernandes, JK Eberhart - Zebrafish, 2016 - liebertpub.com
Abstract Fetal Alcohol Spectrum Disorders (FASD) describes a wide array of ethanol-
induced developmental defects, including craniofacial dysmorphology and cognitive …

Developmental stage and genotype dependent behavioral effects of embryonic alcohol exposure in zebrafish larvae

A Abozaid, L Trzuskot, Z Najmi, I Paul, B Tsang… - Progress in Neuro …, 2020 - Elsevier
Abstract Fetal Alcohol Spectrum Disorders (FASD) represent a worldwide problem. The
severity and types of symptoms of FASD vary, which may be due to the genotype of the fetus …

Zebrafish models of fetal alcohol spectrum disorders

Y Fernandes, CB Lovely - genesis, 2021 - Wiley Online Library
Fetal alcohol spectrum disorder (FASD) describes a wide range of structural deficits and
cognitive impairments. FASD impacts up to 5% of children born in the United States each …

Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder

Y Fernandes, DM Buckley… - Biochemistry and Cell …, 2018 - cdnsciencepub.com
The term fetal alcohol spectrum disorder (FASD) refers to the entire suite of deleterious
outcomes resulting from embryonic exposure to alcohol. Along with other reviews in this …

Strain dependent neurochemical changes induced by embryonic alcohol exposure in zebrafish

S Mahabir, D Chatterjee, R Gerlai - Neurotoxicology and teratology, 2014 - Elsevier
Abstract Fetal Alcohol Spectrum Disorder (FASD) is a preventable disease of the child
resulting from alcohol (ethanol) consumption by pregnant women. Despite being …

Alcohol exposure during embryonic development: An opportunity to conduct systematic developmental time course analyses in zebrafish

A Facciol, B Tsang, R Gerlai - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Ethanol affects numerous neurobiological processes depending upon the developmental
stage at which it reaches the vertebrate embryo. Exposure time dependency may explain the …

Behavioral responses to novelty or to a predator stimulus are not altered in adult zebrafish by early embryonic alcohol exposure

D Seguin, S Shams, R Gerlai - Alcoholism: Clinical and …, 2016 - Wiley Online Library
Background Fetal alcohol spectrum disorders (FASD) may vary in symptoms and severity. In
the milder and more prevalent forms of the disease, behavioral abnormalities may include …

A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors

AR Patten, CJ Fontaine, BR Christie - Frontiers in pediatrics, 2014 - frontiersin.org
Prenatal ethanol exposure (PNEE) has been linked to widespread impairments in brain
structure and function. There are a number of animal models that are used to study the …