There are limited data describing the concentrations of zidovudine, lamivudine, and
nevirapine in nursing infants as a result of transfer via breast milk. The Kisumu …

Background The magnitude of infant antiretroviral (ARV) exposure from breast milk is
unknown Methods We measured concentrations of nevirapine, lamivudine, and zidovudine …

Background: The administration of antiretroviral therapy to lactating women could represent
a possible strategy to reduce postnatal HIV transmission. In this study, we assessed the …

Studying the pharmacokinetics of antiretroviral drugs in breast milk has important
implications for the health of both the mother and the infant, particularly in resource-poor …

Background An intensive, prospective, open-label pharmacokinetic (PK) study in a subset of
HIV-infected mothers and their uninfected infants enrolled in the Breastfeeding, Antiretroviral …

Objectives The objectives of this study were to summarize antiretroviral drug concentrations
in breast milk (BM) and exposure of breast-fed infants. Methods This was a systematic …

Background Limited information is available on anti-retroviral concentrations in
women/infant pairs receiving prophylaxis for breastfeeding transmission of HIV and on the …

Despite the success of antiretroviral prophylaxis in reducing mother-to-child HIV-1
transmission, postpartum transmission through breast milk remains a problem. Antiretroviral …

Objective: To compare the effect of perinatal regimens of short-course nevirapine (HIVNET
012) and zidovudine [Thai-Centers for Disease Control and Prevention (CDC) regimen] on …

Objectives Nevirapine is widely used in the developing world for the prevention of mother-to-
child transmission (PMTCT) of HIV. A single mutation in the HIV genome is sufficient to lead …