Possible adverse effects of food additive E171 (titanium dioxide) related to particle specific human toxicity, including the immune system

NS Bischoff, TM de Kok, DTHM Sijm… - International journal of …, 2020 - mdpi.com
Titanium dioxide (TiO2) is used as a food additive (E171) and can be found in sauces,
icings, and chewing gums, as well as in personal care products such as toothpaste and …

Repeated administration of the food additive E171 to mice results in accumulation in intestine and liver and promotes an inflammatory status

L Talamini, S Gimondi, MB Violatto, F Fiordaliso… - …, 2019 - Taylor & Francis
Titanium dioxide (TiO2) is widely used in pharmaceuticals preparations, cosmetics, and as a
food additive (E171). It contains microparticles and a fraction of nanoparticles (NPs) which …

Toxicological impact of titanium dioxide nanoparticles and food-grade titanium dioxide (E171) on human and environmental health

F Fiordaliso, P Bigini, M Salmona… - Environmental Science …, 2022 - pubs.rsc.org
The widespread use of titanium dioxide (TiO2) as a pigment, mostly in the form of
nanoparticles (NPs), for a variety of applications, arouses increasing concerns about its …

Adverse outcome pathways associated with the ingestion of titanium dioxide nanoparticles—a systematic review

D Rolo, R Assunção, C Ventura, P Alvito, L Gonçalves… - Nanomaterials, 2022 - mdpi.com
Titanium dioxide nanoparticles (TiO2-NPs) are widely used, and humans are exposed
through food (E171), cosmetics (eg, toothpaste), and pharmaceuticals. The oral and …

Titanium dioxide nanoparticles: a risk for human health?

F Grande, P Tucci - Mini reviews in medicinal chemistry, 2016 - ingentaconnect.com
Titanium dioxide (TiO2) is a natural oxide of the element titanium with low toxicity, and
negligible biological effects. The classification as bio-inert material has given the possibility …

Ingestion of titanium dioxide nanoparticles: a definite health risk for consumers and their progeny

R Cornu, A Béduneau, H Martin - Archives of toxicology, 2022 - Springer
Titanium dioxide (TiO2) is one of the most commonly used nanomaterials in the world.
Additive E171, which is used in the food industry, contains a nanometric particle fraction of …

Risk assessment of titanium dioxide nanoparticles via oral exposure, including toxicokinetic considerations

MB Heringa, L Geraets, JCH van Eijkeren… - …, 2016 - Taylor & Francis
Titanium dioxide white pigment consists of particles of various sizes, from which a fraction is
in the nano range (< 100 nm). It is applied in food as additive E 171 as well as in other …

Food additive titanium dioxide and its fate in commercial foods

JS Hwang, J Yu, HM Kim, JM Oh, SJ Choi - Nanomaterials, 2019 - mdpi.com
Titanium dioxide (TiO2) is one of the most extensively utilized food additives (E171) in the
food industry. Along with nanotechnology development, the concern about the presence of …

Review of health safety aspects of titanium dioxide nanoparticles in food application

Z Chen, S Han, S Zhou, H Feng, Y Liu, G Jia - NanoImpact, 2020 - Elsevier
Food grade titanium dioxide (TiO 2) has been widely used as a food additive in the food
industry. Compared to TiO 2 bulk particles, TiO 2 nanoparticles (TiO 2 NPs) has even more …

Criteria to define a more relevant reference sample of titanium dioxide in the context of food: a multiscale approach

W Dudefoi, H Terrisse, M Richard-Plouet… - Food Additives & …, 2017 - Taylor & Francis
Titanium dioxide (TiO2) is a transition metal oxide widely used as a white pigment in various
applications, including food. Due to the classification of TiO2 nanoparticles by the …