[HTML][HTML] Microalgae-based drug delivery system for tumor microenvironment photo-modulating and synergistic chemo-photodynamic therapy of osteosarcoma

F Liang, X An, R Wang, W Wu, L Yang, Y Zheng… - Engineered …, 2024 - Elsevier
Osteosarcoma (OS) is one of the most common malignant tumors in children and young
adults. As chemotherapy and other therapies are limited by low therapeutic efficiency …

Doxorubicin-loaded microalgal delivery system for combined chemotherapy and enhanced photodynamic therapy of osteosarcoma

X An, D Zhong, W Wu, R Wang, L Yang… - … Applied Materials & …, 2024 - ACS Publications
Osteosarcoma (OS) is considered the most frequent type of primary malignant bone tumor.
Currently, radiotherapy, photodynamic (PDT), and other therapies for osteosarcoma are …

Dual‐Stage Light Amplified Photodynamic Therapy against Hypoxic Tumor Based on an O2 Self‐Sufficient Nanoplatform

LH Liu, YH Zhang, WX Qiu, L Zhang, F Gao, B Li, L Xu… - Small, 2017 - Wiley Online Library
Tumor hypoxia severely limits the efficacy of traditional photodynamic therapy (PDT). Here, a
liposome‐based nanoparticle (designated as LipoMB/CaO2) with O2 self‐sufficient property …

Tumor homing-penetrating and nanoenzyme-augmented 2D phototheranostics against hypoxic solid tumors

C Wu, Y Zhang, X Wei, N Li, H Huang, Z Xie, H Zhang… - Acta Biomaterialia, 2022 - Elsevier
Tumor microenvironment (TME)-oriented nanomedicine emerges as an efficient routine to
greatly improve the efficiency of cancer treatment. The typical feature of hypoxia in TME …

Engineering tumor-oxygenated nanomaterials: advancing photodynamic therapy for cancer treatment

T Zuo, X Li, X Ma, Y Zhang, X Li, X Fan… - … in Bioengineering and …, 2024 - frontiersin.org
Photodynamic therapy (PDT), a promising treatment modality, employs photosensitizers to
generate cytotoxic reactive oxygen species (ROS) within localized tumor regions. This …

Multistage tumor microenvironment-responsive theranostic nanopeanuts: toward multimode imaging guided chemo-photodynamic therapy

X Jing, Z Zhi, N Zhang, H Song, Y Xu, G Zhou… - Chemical Engineering …, 2020 - Elsevier
It is of great importance to develop tumor microenvironment (TME) responsive and
adjustable theranostic nano-systems for specific and efficient cancer treatment. However …

Biodegradable hollow manganese silicate nanocomposites to alleviate tumor hypoxia toward enhanced photodynamic therapy

M Nafiujjaman, SJ Chung, I Kalashnikova… - ACS Applied Bio …, 2020 - ACS Publications
Photodynamic therapy (PDT) has been extensively explored as a minimally invasive
treatment strategy for malignant cancers. It works with the help of a photosensitizer located …

[HTML][HTML] Intratibial osteosarcoma growth and pulmonary metastasis inhibition by HIPPO signaling pathway-induced photodynamic therapy

W Wang, J Chang, H Ruan, X Sun, F Zhao, P Zhao… - Materials & Design, 2023 - Elsevier
Cancer is a global leading cause of death, with nearly 10 million people dying from cancer
in 2020. Photodynamic therapy (PDT) has emerged as a promising cancer treatment …

Stereocomplex crystallized nanomedical system for enhanced type i pdt and synergistic chemo-phototherapy

Y Ren, L Mei, C Huang, R Fan, B Chen… - ACS Materials …, 2022 - ACS Publications
Photodynamic therapy (PDT) is one of the promising approaches for tumor treatment.
Although PDT offers many advantages, it is still challenged by the restriction of oxygen and …

A cyclic nano-reactor achieving enhanced photodynamic tumor therapy by reversing multiple resistances

P Liu, Y Zhou, X Shi, Y Yuan, Y Peng, S Hua… - Journal of …, 2021 - Springer
Background Photodynamic therapy (PDT) is a clinically implemented modality to combat
malignant tumor, while its efficacy is largely limited by several resistance factors from tumor …