Maternofetal inflammation induced for 2 wk in late gestation reduced birth weight and impaired neonatal growth and skeletal muscle glucose metabolism in lambs
Intrauterine stress impairs growth and metabolism in the fetus and offspring. We recently
found that sustained maternofetal inflammation resulted in intrauterine growth-restricted (MI …
found that sustained maternofetal inflammation resulted in intrauterine growth-restricted (MI …
Sustained maternal inflammation during the early third-trimester yields intrauterine growth restriction, impaired skeletal muscle glucose metabolism, and diminished β …
CN Cadaret, EM Merrick, TL Barnes… - Journal of animal …, 2019 - academic.oup.com
Maternal inflammation causes fetal intrauterine growth restriction (IUGR), but its impact on
fetal metabolism is not known. Thus, our objective was to determine the impact of sustained …
fetal metabolism is not known. Thus, our objective was to determine the impact of sustained …
Sustained maternal inflammation during the early third trimester yields fetal adaptations that impair subsequent skeletal muscle growth and glucose metabolism in …
CN Cadaret, EM Merrick, TL Barnes… - Translational animal …, 2018 - academic.oup.com
Intrauterine growth restriction (IUGR) is linked to metabolic dysfunction in offspring, but the
mediating mechanisms are still under investigation (Barker et al., 1993). IUGR fetuses adapt …
mediating mechanisms are still under investigation (Barker et al., 1993). IUGR fetuses adapt …
Going up inflame: reviewing the underexplored role of inflammatory programming in stress-induced intrauterine growth restricted livestock
ZM Hicks, DT Yates - Frontiers in Animal Science, 2021 - frontiersin.org
The impact of intrauterine growth restriction (IUGR) on health in humans is well-recognized.
It is the second leading cause of perinatal mortality worldwide, and it is associated with …
It is the second leading cause of perinatal mortality worldwide, and it is associated with …
Intermittent maternofetal oxygenation during late gestation improved birthweight, neonatal growth, body symmetry, and muscle metabolism in intrauterine growth …
CN Cadaret, RJ Posont, RM Swanson… - Journal of animal …, 2022 - academic.oup.com
In humans and animals, intrauterine growth restriction (IUGR) results from fetal programming
responses to poor intrauterine conditions. Chronic fetal hypoxemia elevates circulating …
responses to poor intrauterine conditions. Chronic fetal hypoxemia elevates circulating …
Maternal inflammation at midgestation impairs subsequent fetal myoblast function and skeletal muscle growth in rats, resulting in intrauterine growth restriction at term
CN Cadaret, RJ Posont, KA Beede… - Translational animal …, 2019 - academic.oup.com
Maternal inflammation induces intrauterine growth restriction (MI-IUGR) of the fetus, which
compromises metabolic health in human offspring and reduces value in livestock. The …
compromises metabolic health in human offspring and reduces value in livestock. The …
Up-regulation of Toll-like receptor 4/nuclear factor-κB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese …
Maternal obesity is increasing at an alarming rate. We previously showed that maternal
obesity induces an inflammatory response and enhances adipogenesis in fetal skeletal …
obesity induces an inflammatory response and enhances adipogenesis in fetal skeletal …
Primary myoblasts from intrauterine growth-restricted fetal sheep exhibit intrinsic dysfunction of proliferation and differentiation that coincides with enrichment of …
Intrauterine growth restriction (IUGR) is linked to lifelong reductions in muscle mass due to
intrinsic functional deficits in myoblasts, but the mechanisms underlying these deficits are …
intrinsic functional deficits in myoblasts, but the mechanisms underlying these deficits are …
Decreased fetal biometrics and impaired β-cell function in IUGR fetal sheep are improved by daily ω-3 PUFA infusion
TA Lacey, RL Gibbs, MS Most, HN Beer… - Translational Animal …, 2021 - academic.oup.com
Placental insufficiency-induced intrauterine growth restriction (IUGR) results in muscle-
centric fetal programming that impairs glucose metabolism (Yates et al., 2019) and yields …
centric fetal programming that impairs glucose metabolism (Yates et al., 2019) and yields …
Daily Injection of the β2 Adrenergic Agonist Clenbuterol Improved Muscle Glucose Metabolism, Glucose-Stimulated Insulin Secretion, and Hyperlipidemia in Juvenile …
RL Gibbs, JA Wilson, RM Swanson, JK Beard… - Metabolites, 2024 - mdpi.com
Stress-induced fetal programming diminishes β2 adrenergic tone, which coincides with
intrauterine growth restriction (IUGR) and lifelong metabolic dysfunction. We determined if …
intrauterine growth restriction (IUGR) and lifelong metabolic dysfunction. We determined if …
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