Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …

Aquaporins (AQPs) represent a diverse family of membrane proteins found in prokaryotes
and eukaryotes. The primary aquaporins expressed in the mammalian brain are AQP1 …

Aquaporin-4 (AQP4) is expressed in astrocytes throughout the central nervous system,
particularly at the blood–brain and brain–cerebrospinal fluid barriers. Phenotype analysis of …

Emerging evidence suggests that brain aquaporins (AQP) play important roles for the
dynamic regulation of brain water homeostasis and for the regulation of cerebrospinal fluid …

Summary Aquaporin 4 (AQP 4) is the main water channel in the central nervous system
(CNS) and specifically localized to astrocyte processes. Recent studies indicate that AQP 4 …

Water homeostasis in the brain is of central physiologic and clinical importance. Neuronal
activity and ion water homeostasis are inextricably coupled. For example, the clearance of …

Since the discovery of aquaporins, it has become clear that the various mammalian
aquaporins play critical physiological roles in water and ion balance in multiple tissues …

ABSTRACT Aquaporin‐4 (AQP4), the main water channel in the brain, is expressed in the
perivascular membranes of mouse, rat, and human astrocytes. In a previous study, we used …

Aquaporin-4 (AQP4) is the predominant water channel in the neuropil of the central nervous
system. It is expressed primarily in astrocytes, but also occurs in ependymocytes and …

Aquaporin-4 (AQP4) is a water channel expressed on astrocytic endfeet in the brain. The
role of AQP4 has been studied in health and in a range of pathological conditions. Interest in …