Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin

R Ginwala, R Bhavsar, DGI Chigbu, P Jain, ZK Khan - Antioxidants, 2019 - mdpi.com
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …

Apigenin, a natural flavonoid, attenuates EAE severity through the modulation of dendritic cell and other immune cell functions

R Ginwala, E McTish, C Raman, N Singh… - Journal of neuroimmune …, 2016 - Springer
Apigenin, a natural flavonoid, found in several plants, fruits, vegetables, herbs, and spices, is
known to have anti-oxidant and anti-inflammatory properties that are evident in the use of …

Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease

A García-Lafuente, E Guillamón, A Villares… - Inflammation …, 2009 - Springer
Chronic inflammation is being shown to be increasingly involved in the onset and
development of several pathological disturbances such as arteriosclerosis, obesity …

Proinflammatory pathways: the modulation by flavonoids

D Ribeiro, M Freitas, JLFC Lima… - Medicinal research …, 2015 - Wiley Online Library
Inflammation is a natural, carefully orchestrated response of the organism to tissue damage,
involving various signaling systems and the recruitment of inflammatory cells. These cells …

Flavonoids as potential anti-inflammatory molecules: A review

JM Al-Khayri, GR Sahana, P Nagella, BV Joseph… - Molecules, 2022 - mdpi.com
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits,
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …

Anti-inflammatory effects of flavonoids in neurodegenerative disorders

C Spagnuolo, S Moccia, GL Russo - European journal of medicinal …, 2018 - Elsevier
Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …

[HTML][HTML] Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer's …

NS Dourado, CS Souza, MMA De Almeida… - Frontiers in Aging …, 2020 - frontiersin.org
Neurodegenerative disorders (ND) are characterized by the progressive and irreversible
loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the …

Anti-inflammatory activity of natural dietary flavonoids

MH Pan, CS Lai, CT Ho - Food & function, 2010 - pubs.rsc.org
Over the past few decades, inflammation has been recognized as a major risk factor for
various human diseases. Acute inflammation is short-term, self-limiting and it's easy for host …

Role of flavonoids in management of inflammatory disorders

R Shukla, V Pandey, GP Vadnere, S Lodhi - Bioactive food as dietary …, 2019 - Elsevier
Flavonoids are a wide category of polyphenolic compounds that have a major role in the
treatment of various inflammatory diseases, including arthritis, gastritis, nephritis, hepatitis …

Apigenin: A natural bioactive flavone-type molecule with promising therapeutic function

D Kashyap, A Sharma, HS Tuli, K Sak, VK Garg… - Journal of Functional …, 2018 - Elsevier
There exist overwhelming evidence that plant-derived bioactive flavonoids possess strong
therapeutic activities against cancer, cardiovascular diseases, and age-related …