Prostate cancer (PCa) has been known as the most prevalent cancer disease and the
second leading cause of cancer mortality in men almost all over the globe. There is an …

Prostate cancer (PC) is the most prevalent cancer in men and the second main cause of
cancer-related death in Western society. The lack of proper PC models that recapitulate the …

Complex heterogeneity is an important characteristic in the development of prostate cancer
(PCa), which further leads to the failure of known therapeutic options. PCa research has …

One of the major goals in the advancement of basic cancer research focuses on the
development of new anticancer therapies. To understand the molecular mechanisms of …

Background Current in vitro modeling systems do not fully reflect the biologic and clinical
diversity of prostate cancer (PCa). Organoids are 3D in vitro cell cultures that recapitulate …

A key challenge in the clinical management and cause of treatment failure of prostate cancer
(PCa) is its molecular, cellular and clinical heterogeneity. Modelling systems that fully …

Organoids are self-organized cellular clusters in three-dimensional culture, which can be
derived from a single stem cell, progenitor or cell clusters of different lineages resembling in …

Organoid technology has provided new translational research opportunities in oncology, in
part by enabling the development of patient-representative living biobanks. Prostate cancer …

Urological cancers such as kidney, bladder, prostate, and testicular cancers are the most
common types of cancers worldwide with high mortality and morbidity. To date, traditional …

Prostate cancer (PCa) is the second most common malignancy and the fifth leading cause of
cancer death in men worldwide. Despite its prevalence, the highly heterogenic PCa has …