The toxicity of cancer chemotherapy is among the most important factors limiting its use.
Clear delineation and communication of benefits and risks is an essential component of …

Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …

Chemotherapy-induced toxicities commonly occur in sites within the gastrointestinal (GI)
tract and account for dose-limiting effects. These toxicities are major contributing factors to …

There are many anti-neoplastic agents in cancer treatment. Combination regimens are often
the main standard treatment, particularly for gastrointestinal malignancies. The introduction …

Gastrointestinal complications are common in patients undergoing various forms of cancer
treatment, including chemotherapy, radiation therapy, and molecular-targeted therapies …

Mucosal injury induced by radiation or chemotherapy is a common, painful, function
disrupting toxicity that, currently, has limited treatment options. The evolving understanding …

Cancer survival rates have significantly improved over the last number of years due to
advancements in cancer therapies. Unfortunately this has come at a cost. Therapeutic side …

Gastrointestinal toxicities (GIT), including oral mucositis, nausea and vomiting, and diarrhea,
are common side effects of chemotherapy and targeted agents in patients with advanced …

The anticancer agents fluorouracil, raltitrexed, irinotecan and oxaliplatin show limited
efficacy in the treatment of colorectal cancer and may be associated with substantial toxicity …

Among the many chemotherapeutic options for metastatic colorectal cancer, none has
shown clear superiority in efficacy. All pharmacologic agents in current use have been …