Ferroptosis and cell death mechanisms in Parkinson's disease
Symptoms of Parkinson's disease arise due to neuronal loss in multiple brain regions,
especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies …
especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies …
Ferroptosis and its potential role in the physiopathology of Parkinson's Disease
L Mahoney-Sánchez, H Bouchaoui, S Ayton… - Progress in …, 2021 - Elsevier
Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …
characterised by motor impairments as well as non-motor symptoms. While dopamine …
Ferroptosis in Parkinson's disease: Molecular mechanisms and therapeutic potential
X Ding, L Gao, Z Han, S Eleuteri, W Shi, Y Shen… - Ageing research …, 2023 - Elsevier
Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …
[HTML][HTML] Ferroptosis in Parkinson's disease: glia–neuron crosstalk
ZL Wang, L Yuan, W Li, JY Li - Trends in molecular medicine, 2022 - cell.com
Parkinson's disease (PD) is characterized by dopaminergic (DA) neuron loss and the
formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is …
formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is …
Novel druggable mechanism of Parkinson's disease: potential therapeutics and underlying pathogenesis based on ferroptosis
Genetics, age, environmental factors, and oxidative stress have all been implicated in the
development of Parkinson's disease (PD); however, a complete understanding of its …
development of Parkinson's disease (PD); however, a complete understanding of its …
Iron brain menace: the involvement of ferroptosis in Parkinson disease
KJ Lin, SD Chen, KL Lin, CW Liou, MY Lan… - Cells, 2022 - mdpi.com
Parkinson disease (PD) is the second-most common neurodegenerative disease. The
characteristic pathology of progressive dopaminergic neuronal loss in people with PD is …
characteristic pathology of progressive dopaminergic neuronal loss in people with PD is …
Therapeutic insights on ferroptosis in Parkinson's disease
Parkinson's disease (PD) is a neurodegenerative disorder that alters either motor or non-
motor activities. Dopamine-based medications can help alleviate symptoms at an early …
motor activities. Dopamine-based medications can help alleviate symptoms at an early …
Ferroptosis as a major factor and therapeutic target for neuroinflammation in Parkinson's disease
Mounting evidence suggests that ferroptosis is not just a consequence but also a
fundamental contributor to the development and progression of Parkinson's disease (PD) …
fundamental contributor to the development and progression of Parkinson's disease (PD) …
Research progress in the molecular mechanism of ferroptosis in Parkinson's disease and regulation by natural plant products
K Yang, L Zeng, J Zeng, Y Deng, S Wang, H Xu… - Ageing Research …, 2023 - Elsevier
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder of the
central nervous system after Alzheimer's disease. The current understanding of PD focuses …
central nervous system after Alzheimer's disease. The current understanding of PD focuses …
Ferroptosis: A potential therapeutic target for neurodegenerative diseases
D Vitalakumar, A Sharma… - Journal of Biochemical …, 2021 - Wiley Online Library
Ferroptosis is a newly identified regulated form of cell death, which is thought to play a major
role in neurodegenerative diseases. In this review, we discuss recent studies elucidating the …
role in neurodegenerative diseases. In this review, we discuss recent studies elucidating the …
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