Coupling microdroplet microreactors with mass spectrometry: reading the contents of single droplets online

LM Fidalgo, G Whyte, BT Ruotolo… - Angewandte …, 2009 - Wiley Online Library
Emulsions created inside microfluidic devices have generated significant interest in recent
years because of their ability to compartmentalize reactions and assays on a microfluidic …

[PDF][PDF] From microdroplets to microfluidics: selective emulsion separation in microfluidic devices

LM Fidalgo, G Whyte, D Bratton… - Angewandte Chemie …, 2008 - laser.ceb.cam.ac.uk
Microdroplets show great promise as a new high-throughput technology in chemistry,
biochemistry, and molecular biology.[1–3] Microdroplets can be generated at rates in excess …

Microdroplets in microfluidics: an evolving platform for discoveries in chemistry and biology

AB Theberge, F Courtois, Y Schaerli… - Angewandte Chemie …, 2010 - Wiley Online Library
Microdroplets in microfluidics offer a great number of opportunities in chemical and
biological research. They provide a compartment in which species or reactions can be …

[引用][C] Microfluidics with droplets

D Belder - Angewandte Chemie International Edition, 2005 - Wiley Online Library
In analogy to miniaturization in microelectronics, the integration of chemical processes on
chips, where chemical reactions are performed in microchannels and-cavities, is currently …

Droplet-based microfluidics

T Moragues, D Arguijo, T Beneyton, C Modavi… - Nature Reviews …, 2023 - nature.com
Droplet-based microfluidic systems generate, manipulate and control sub-microlitre droplets
enclosed within an immiscible carrier fluid. Owing to a number of remarkable features, such …

Microdroplet-assisted screening of biomolecule production for metabolic engineering applications

EK Bowman, HS Alper - Trends in biotechnology, 2020 - cell.com
Success in synthetic biology and metabolic engineering is quickly becoming 'test'limited
within the design–build–test cycle. Commonly used methods for high-throughput screening …

Droplet microfluidics: recent developments and future applications

XC i Solvas, A DeMello - Chemical Communications, 2011 - pubs.rsc.org
We report recent advances in the field of droplet-based microfluidics. Specifically, we
highlight the unique features of such platforms for high-throughput experimentation; …

[HTML][HTML] Dilution-free analysis from picoliter droplets by Nano-ESI MS

RT Kelly, JS Page, I Marginean, K Tang… - … (International ed. in …, 2009 - ncbi.nlm.nih.gov
The amount of sample required for a chemical analysis is frequently determined not by
instrument sensitivity but by the ability to isolate, prepare and deliver trace analytes to the …

On‐chip spyhole mass spectrometry for droplet‐based microfluidics

N Gasilova, Q Yu, L Qiao, HH Girault - Angewandte Chemie, 2014 - Wiley Online Library
For efficient coupling of droplet‐based microfluidics with mass spectrometry (MS), a spyhole
drilled on the top of a microchip is used to sample the passing droplets by electrostatic …

Reactions in droplets in microfluidic channels

H Song, DL Chen, RF Ismagilov - … chemie international edition, 2006 - Wiley Online Library
Fundamental and applied research in chemistry and biology benefits from opportunities
provided by droplet‐based microfluidic systems. These systems enable the miniaturization …