Simple Summary Chemotherapy is becoming an increasingly difficult antitumor therapy to
practice due to the multiple mechanisms of drug resistance. To overcome the problem, it is …

Tumor microenvironment is one of the major obstacles to the efficacy of chemotherapy in
cancer patients. The abnormal blood flow within the tumor results in uneven drug …

Electrochemotherapy is gaining recognition as an effective local therapy that uses
systemically or intratumorally injected bleomycin or cisplatin with electroporation as a …

Electrochemotherapy consists of chemotherapy followed by local application of electric
pulses to the tumour to increase drug delivery into cells. Drug uptake can be increased by …

The curative effects of some chemotherapeutic drugs are impeded by their poor permeation
through the cell membrane. This limitation can be overcome by a novel approach called …

Electrochemotherapy is a tumor treatment that adapts the systemic or local delivery of
anticancer drugs by the application of permeabilizing electric pulses with appropriate …

Electrochemotherapy combines administration of nonpermeant or poorly permeant
chemotherapeutic drugs with application of electric pulses to the tumors in order to facilitate …

Treatment of recurrent or unresectable cutaneous and subcutaneaous tumors continues to
be a major therapeutic challenge. Electrochemotherapy (ECT) is a palliative treatment of …

Simple Summary Electrochemotherapy (ECT) was first introduced in the late 1980s and was
initially used mainly on cutaneous tumors. It has now evolved into a clinically verified …

Electrochemotherapy is currently undergoing intensive investigation in the field of local
control of cancer. In Greece, five medical centers have co-operated to perform ECT for the …