Dengue virus and the host innate immune response

N Uno, TM Ross - Emerging microbes & infections, 2018 - Taylor & Francis
Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and
sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There …

Innate immunity evasion by Dengue virus

J Morrison, S Aguirre, A Fernandez-Sesma - Viruses, 2012 - mdpi.com
For viruses to productively infect their hosts, they must evade or inhibit important elements of
the innate immune system, namely the type I interferon (IFN) response, which negatively …

Innate immunity to dengue virus infection and subversion of antiviral responses

AM Green, PR Beatty, A Hadjilaou, E Harris - Journal of molecular biology, 2014 - Elsevier
Dengue is a major public health issue in tropical and subtropical regions worldwide. The
four serotypes of dengue virus (DENV1–DENV4) are spread primarily by Aedes aegypti and …

Innate immune escape by Dengue and West Nile viruses

MU Gack, MS Diamond - Current opinion in virology, 2016 - Elsevier
Highlights•RLR-, TLR-and cGAS/STING-dependent pathways restrict DENV and WNV
infection.•DENV and WNV sequester or modify their RNA to avoid detection by innate …

Immune-mediated pathogenesis in dengue virus infection

A Khanam, H Gutiérrez-Barbosa, KE Lyke, JV Chua - Viruses, 2022 - mdpi.com
Dengue virus (DENV) infection is one of the major public health concerns around the globe,
especially in the tropical regions of the world that contribute to 75% percent of dengue …

Dengue virus infection: a tale of viral exploitations and host responses

N Nanaware, A Banerjee, S Mullick Bagchi, P Bagchi… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …

Innate and adaptive immune evasion by dengue virus

MF Lee, GZ Voon, HX Lim, ML Chua… - Frontiers in Cellular and …, 2022 - frontiersin.org
Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …

Mobilization and activation of the innate immune response to dengue virus

CA King, AD Wegman, TP Endy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Dengue virus is an important human pathogen, infecting an estimated 400 million
individuals per year and causing symptomatic disease in a subset of approximately 100 …

The battle between infection and host immune responses of dengue virus and its implication in dengue disease pathogenesis

P Sun, TJ Kochel - The Scientific World Journal, 2013 - Wiley Online Library
Dengue virus (DENV) is a mosquito‐transmitted single stranded RNA virus belonging to
genus Flavivirus. The virus is endemic in the tropical and subtropical countries of the world …

Dysfunctional innate immune responses and severe dengue

GN Malavige, C Jeewandara, GS Ogg - Frontiers in cellular and …, 2020 - frontiersin.org
Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild
self-limiting illness in the majority of individuals. There is emerging evidence that an …