[HTML][HTML] Synovial tissue metabolomic profiling reveal biomarkers of synovial inflammation in patients with osteoarthritis

JD Murillo-Saich, R Coras, R Meyer, C Llorente… - … and cartilage open, 2022 - Elsevier
Objective Inflammatory responses are associated with changes in tissue metabolism. Prior
studies find altered metabolomic profiles in both the synovial fluid (SF) and serum of …

Application of global metabolomic profiling of synovial fluid for osteoarthritis biomarkers

AK Carlson, RA Rawle, E Adams… - Biochemical and …, 2018 - Elsevier
Osteoarthritis affects over 250 million individuals worldwide. Currently, there are no options
for early diagnosis of osteoarthritis, demonstrating the need for biomarker discovery. To find …

[HTML][HTML] Characterization of synovial fluid metabolomic phenotypes of cartilage morphological changes associated with osteoarthritis

AK Carlson, RA Rawle, CW Wallace, EG Brooks… - Osteoarthritis and …, 2019 - Elsevier
Objective Osteoarthritis (OA) is a multifactorial disease with etiological heterogeneity. The
objective of this study was to classify OA subgroups by generating metabolomic phenotypes …

Utilizing metabolomics to identify potential biomarkers and perturbed metabolic pathways in osteoarthritis: A systematic review

PM Van Pevenage, JT Birchmier, RK June - Seminars in arthritis and …, 2023 - Elsevier
Purpose Osteoarthritis (OA) is a joint disease that is clinically diagnosed using components
of history, physical exam, and characteristic radiographic findings, such as joint space …

[HTML][HTML] Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis

R Narasimhan, R Coras, SB Rosenthal… - Arthritis research & …, 2018 - Springer
Background Metabolomics is an emerging field of biomedical research that may offer a
better understanding of the mechanisms of underlying conditions including inflammatory …

Global and targeted metabolomics of synovial fluid discovers special osteoarthritis metabolites

K Zheng, N Shen, H Chen, S Ni, T Zhang… - Journal of …, 2017 - Wiley Online Library
To identify special metabolites in synovial fluid of osteoarthritis (OA) via a metabolomics
approach. Synovial fluid of 35 participants (25 OA patients and 10 controls) was detected by …

Correlations between metabolites in the synovial fluid and serum: A mouse injury study

CW Wallace, B Hislop, AK Hahn… - Journal of …, 2022 - Wiley Online Library
Osteoarthritis occurs frequently after joint injury. Currently, osteoarthritis is diagnosed by
radiographic changes that are typically found after the disease has progressed to multiple …

Normal and osteoarthritic synovial fluid present different metabolomic profile

EB de Sousa, GC de Farias… - Osteoarthritis and …, 2017 - oarsijournal.com
Purpose: Investigate the metabolomic profile of synovial fluid from patients with and without
knee osteoarthritis (OA), in order to identify new metabolic markers for therapeutic targets …

[HTML][HTML] The role of metabolomics in precision medicine of osteoarthritis: How far are we?

G Zhai - Osteoarthritis and Cartilage Open, 2021 - Elsevier
Objectives A narrative review on recent published studies of metabolomics in osteoarthritis
(OA) with the focus on how the metabolomic findings help stratify OA patients in precision …

[PDF][PDF] Global metabolomic profiling of human synovial fluid for rheumatoid arthritis biomarkers

AK Carlson, RA Rawle, CW Wallace… - Clin Exp …, 2019 - clinexprheumatol.org
Global metabolomic profiling of human synovial fluid for rheumatoid arthritis biomarkers
Page 1 Clinical and Experimental Rheumatology 2019 Clinical and Experimental …