Simple Summary Colorectal cancer (CRC) is a leading cause of death among cancer
patients, and the liver is the most common visceral metastatic site. Despite promising …

In patients with colorectal cancer (CRC) that metastasizes to the liver, there are several key
goals for improving outcomes including early detection, effective prognostic indicators of …

Simple Summary Colorectal cancer remains one of the most significant sources of cancer-
related morbidity and mortality worldwide. The liver is the most common site of metastatic …

Liver metastases are the most common site of metastatic spread in colorectal cancer.
Current treatment approaches involve effective systemic therapies in combination with …

Colorectal liver metastases (CRLM) are the leading cause of death among patients with
metastatic colorectal cancer (CRC). As part of multimodal therapy, liver resection is the …

Efforts to combat colorectal cancer have benefited from improved screening and
surveillance, which facilitates early detection. The survival rate associated with diagnosis at …

Colorectal liver metastases (CRLM) present an important clinical challenge in both surgical
and medical oncology. Despite improvements in management, survival among patients …

Even though liver metastasis accounts for the vast majority of cancer deaths in patients with
colorectal cancer (CRC), fundamental questions about the molecular and cellular …

Importance Personalized treatment approaches for patients with oligometastatic colorectal
liver metastases are critically needed. We previously defined 3 biologically distinct …

Abstract Background Precision Medicine Initiative is a new research effort aiming to offer
personalized treatment in many diseases, including cancer. The aim of the present article is …