Second harmonic imaging of nasal, auricular, and costal cartilage

KK Dilley, A Lal, TV Nguyen, BJF Wong - The Laryngoscope, 2023 - Wiley Online Library
Objective There is little knowledge about the histological organization of facial and costal
cartilages in terms of matrix structure and cell morphology. Second harmonic generation …

Second harmonic generation imaging in tissue engineering and cartilage pathologies

M Lilledahl, M Olderøy, A Finnøy… - … Microscopy in the …, 2015 - spiedigitallibrary.org
The second harmonic generation from collagen is highly sensitive to what extent collagen
molecules are ordered into fibrils as the SHG signal is approximately proportional to the …

Quantification of collagen distributions in rat hyaline and fibro cartilages based on second harmonic generation imaging

X Zhu, C Liao, Z Wang, S Zhuo, W Liu… - Optics in Health Care …, 2016 - spiedigitallibrary.org
Hyaline cartilage is a semitransparent tissue composed of proteoglycan and thicker type II
collagen fibers, while fibro cartilage large bundles of type I collagen besides other territorial …

Second harmonic generation imaging reveals a distinct organization of collagen fibrils in locations associated with cartilage growth

A Finnøy, K Olstad, MB Lilledahl - Connective tissue research, 2016 - Taylor & Francis
Purpose: The articular-epiphyseal cartilage complex (AECC) is responsible for the
expansion of the bone ends and serves the function of the articular cartilage in juvenile …

Quantification of collagen fiber organization in biological tissues at cellular and molecular scales using second-harmonic generation imaging

R Ambekar Ramachandra Rao - 2012 - ideals.illinois.edu
Collagen is the most abundant structural protein found in the human body, and is
responsible for providing structure and function to tissues. Collagen molecules organize …

Imaging and modeling collagen architecture from the nano to micro scale

CP Brown, MA Houle, K Popov, M Nicklaus… - Biomedical optics …, 2013 - opg.optica.org
The collagen meshwork plays a central role in the functioning of a range of tissues including
cartilage, tendon, arteries, skin, bone and ligament. Because of its importance in function, it …

3D second harmonic generation imaging tomography by multi-view excitation

KR Campbell, B Wen, EM Shelton, R Swader, BL Cox… - Optica, 2017 - opg.optica.org
Biological tissues have complex 3D collagen fiber architecture that cannot be fully visualized
by conventional second harmonic generation (SHG) microscopy due to electric dipole …

Quantitative differentiation of normal and scarred tissues using second‐harmonic generation microscopy

M Yildirim, KP Quinn, JB Kobler, SM Zeitels… - …, 2016 - Wiley Online Library
The aim of this study was to differentiate normal and scarred hamster cheek pouch samples
by applying a quantitative image analysis technique for determining collagen fiber direction …

Study of collagen remodeling in structural disorders of the temporomandibular joint using second-harmonic generation microscopy

J Zhang, J Chen, Y Wang, R Li - Applied Optics, 2021 - opg.optica.org
Structural disorder of the temporomandibular joint (TMJ) is a progressive disease with poor
prognosis due to its physiological three-dimensional anatomical position and the …

Quantification of collagen I in airway tissues using second harmonic generation

G Tjin, P Xu, SH Kable, EPW Kable… - Journal of biomedical …, 2014 - spiedigitallibrary.org
Extracellular matrix (ECM) remodeling contributes to the pathogenic changes in chronic
obstructive pulmonary disease (COPD) and is both complex and not well understood …