Recently there is increasing concern over the association between sleep deprivation (S-
Dep) and depression. Mounting evidence suggests that S-Dep might be a risk factor for …

Curtailment of sleep in modern society leads to a spectrum of neuropsychiatric disorders.
However, the molecular mechanisms underlying the effects of sleep deprivation (SD) remain …

Sleep deprivation (SD) is a powerful antidepressant treatment that shows antidepressant
responses within hours in 40–60% of depressed patients. In more than 80% of responders …

Myocardial infarction (MI) in rats is followed by a behavioral syndrome similar to human post-
MI depression. We tested the effects of escitalopram, a selective serotonin reuptake inhibitor …

Sleep is an essential physiological process for maintaining physical, mental, and emotional
health. Sleep deprivation and associated disorders like depression and anxiety are one of …

Sleep deprivation can exert antidepressant effects in humans in less than 24 h, making it the
fastest acting antidepressant treatment. However, it is rarely used clinically because the …

The selective α2-adrenergic receptor agonist dexmedetomidine acts as an analgesic,
sedative, and anesthetic adjuvant. The most common consequence of sleep deprivation is …

Background Sleep deprivation (SD) has been suggested to have a rapid antidepressant
effect. There is substantial evidence that neuroinflammation and neuroplasticity play critical …

Background: Over the last few years, the number of people suffering from sleeping disorders
has increased significantly despite negative effects on cognition and an association with …

Previous investigations have shown that REM sleep deprivation impairs the hippocampus‐
dependent memory, long-term potentiation and causing mood changes. The aim of the …