Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives
JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …
Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications
A Caturano, M D'Angelo, A Mormone, V Russo… - Current Issues in …, 2023 - mdpi.com
Oxidative stress is a critical factor in the pathogenesis and progression of diabetes and its
associated complications. The imbalance between reactive oxygen species (ROS) …
associated complications. The imbalance between reactive oxygen species (ROS) …
Oxidative stress and diabetes: antioxidative strategies
Diabetes mellitus is one of the major public health problems worldwide. Considerable recent
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …
Diabetes, oxidative stress and therapeutic strategies
L Rochette, M Zeller, Y Cottin, C Vergely - Biochimica et Biophysica Acta …, 2014 - Elsevier
Background Diabetes has emerged as a major threat to health worldwide. Scope of Review
The exact mechanisms underlying the disease are unknown; however, there is growing …
The exact mechanisms underlying the disease are unknown; however, there is growing …
Diabetic complications and oxidative stress: A 20-year voyage back in time and back to the future
Twenty years have passed since Brownlee and colleagues proposed a single unifying
mechanism for diabetic complications, introducing a turning point in this field of research …
mechanism for diabetic complications, introducing a turning point in this field of research …
Role of oxidative stress in diabetes-induced complications and their management with antioxidants
H Singh, R Singh, A Singh, H Singh… - … of Physiology and …, 2023 - Taylor & Francis
Diabetes mellitus (DM) is a huge global health issue and one of the most studied diseases,
with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive …
with a large global prevalence. Oxidative stress is a cytotoxic consequence of the excessive …
Oxidative stress in diabetes
K Stadler - Diabetes: An Old Disease, a New Insight, 2013 - Springer
Oxidative stress and diabetes, both Type 1 and Type 2 as well as their related conditions
have been extensively studied. As diabetes, obesity and metabolic syndrome have reached …
have been extensively studied. As diabetes, obesity and metabolic syndrome have reached …
Reactive oxygen species: sources, consequences and targeted therapy in type 2 diabetes
SK Panigrahy, R Bhatt, A Kumar - Journal of drug targeting, 2017 - Taylor & Francis
Oxidative stress has been considered as a central mediator in the progression of diabetic
complication. The intracellular reactive oxygen species (ROS) leads to oxidative stress and it …
complication. The intracellular reactive oxygen species (ROS) leads to oxidative stress and it …
Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …
biochemical processes leading to elevated production of reactive oxygen species (ROS) …
Reactive species and diabetes: counteracting oxidative stress to improve health
P Pérez-Matute, MA Zulet, JA Martínez - Current opinion in pharmacology, 2009 - Elsevier
Oxidative stress is at the very core of metabolism. Reactive species behave as true second
messengers that control important cellular functions. However, under pathological …
messengers that control important cellular functions. However, under pathological …