Mass spectrometry imaging (MSI) is a powerful, label-free technique that provides detailed
maps of hundreds of molecules in complex samples with high sensitivity and subcellular …

Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Mass spectrometry (MS) imaging links molecular information and the spatial distribution of
analytes within a sample. In contrast to most histochemical techniques, mass spectrometry …

Over the last two decades, mass spectrometry imaging (MSI) has been increasingly
employed to investigate the spatial distribution of a wide variety of molecules in complex …

The ability of mass spectrometry imaging (MSI) to localize panels of biomolecules in tissues,
without prior knowledge of their presence and in a label-free manner, has led to a rapid and …

MS imaging (MSI) is a remarkable new technology that enables us to determine the
distribution of biological molecules present in tissue sections by direct ionization and …

Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …

Imaging mass spectrometry is currently receiving a significant amount of attention in the
mass spectrometric community. It offers the potential of direct examination of biomolecular …

Mass spectrometric imaging allows the investigation of the spatial distribution of molecules
at complex surfaces. The combination of molecular speciation with local analysis renders a …

Highlights•IMS improves analytical performance of MS imaging of biological tissue
samples.•Improvements in specificity and imaging accuracy are achieved for small …