EPA prevents fat mass expansion and metabolic disturbances in mice fed with a Western diet [S]

A Pinel, E Pitois, JP Rigaudiere, C Jouve… - Journal of lipid …, 2016 - ASBMB
The impact of alpha linolenic acid (ALA), EPA, and DHA on obesity and metabolic
complications was studied in mice fed a high-fat, high-sucrose (HF) diet. HF diets were …

[HTML][HTML] Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation

NS Kalupahana, K Claycombe, SJ Newman… - The Journal of …, 2010 - Elsevier
We investigated the effects of eicosapentaenoic acid (EPA) on prevention (P) and reversal
(R) of high saturated-fat (HF) diet-induced obesity and glucose-insulin homeostasis. Male …

Corn oil versus lard: Metabolic effects of omega-3 fatty acids in mice fed obesogenic diets with different fatty acid composition

J Pavlisova, K Bardova, B Stankova, E Tvrzicka… - Biochimie, 2016 - Elsevier
Mixed results have been obtained regarding the level of insulin resistance induced by high-
fat diets rich in saturated fatty acids (SFA) when compared to those enriched by …

Antiobesity effect of eicosapentaenoic acid in high-fat/high-sucrose diet–induced obesity: importance of hepatic lipogenesis

A Sato, H Kawano, T Notsu, M Ohta, M Nakakuki… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Given the pleiotropic effect of eicosapentaenoic acid (EPA), it is interesting to
know whether EPA is capable of improving obesity. Here we examined the anti-obesity …

[HTML][HTML] Eicosapentaenoic acid reduces adipocyte hypertrophy and inflammation in diet-induced obese mice in an adiposity-independent manner

MJ LeMieux, NS Kalupahana, S Scoggin… - The Journal of …, 2015 - Elsevier
Background: Obesity is associated with an overexpansion of adipose tissue, along with
increases in blood pressure, glycemia, inflammation, and thrombosis. Research to develop …

Linoleic acid causes greater weight gain than saturated fat without hypothalamic inflammation in the male mouse

KJ Mamounis, A Yasrebi, TA Roepke - The Journal of nutritional …, 2017 - Elsevier
A significant change in the Western diet, concurrent with the obesity epidemic, was a
substitution of saturated fatty acids with polyunsaturated, specifically linoleic acid (LA) …

Anti-obesity effects of DHA and EPA in high fat-induced insulin resistant mice

W Wei, M Hu, J Huang, S Yu, X Li, Y Li, L Mao - Food & Function, 2021 - pubs.rsc.org
Docosahexaenoic acid (DHA, 22: 6) and eicosapentaenoic acid (EPA, 20: 5) have been
reported to improve metabolic disorders, but their differential effects on anti-obesity under …

EPA/DHA and linseed oil have different effects on liver and adipose tissue in rats fed with a high-fat diet

BV Dias, SV Gomes, ML da Cruz Castro… - Prostaglandins & Other …, 2022 - Elsevier
The incidence of cardiovascular diseases and metabolic disorders has increased
worldwide. Clinical and experimental research has shown that the consumption of ω-3 FAs …

Long-term dietary supplementation with saury oil attenuates metabolic abnormalities in mice fed a high-fat diet: combined beneficial effect of omega-3 fatty acids and …

ZH Yang, S Inoue, Y Taniguchi, H Miyahara… - Lipids in health and …, 2015 - Springer
Background Pacific saury is a common dietary component in East Asia. Saury oil contains
considerable levels of n-3 unsaturated fatty acids (PUFA) and long-chain monounsaturated …

A diet high in α-linolenic acid and monounsaturated fatty acids attenuates hepatic steatosis and alters hepatic phospholipid fatty acid profile in diet-induced obese rats

D Hanke, P Zahradka, SK Mohankumar… - … and Essential Fatty …, 2013 - Elsevier
This study investigated the efficacy of the plant-based n− 3 fatty acid, α-linolenic acid (ALA),
a dietary precursor of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), for …