Update on gastric cancer treatments and gene therapies

A Biagioni, I Skalamera, S Peri, N Schiavone… - Cancer and Metastasis …, 2019 - Springer
Gastric cancer is an active topic of clinical and basic research due to high morbidity and
mortality. To date, gastrectomy and chemotherapy are the only therapeutic options for gastric …

Application of CRISPR/Cas9 gene editing technique in the study of cancer treatment

C Jiang, L Meng, B Yang, X Luo - Clinical genetics, 2020 - Wiley Online Library
In recent years, gene editing, especially that using clustered regularly interspaced short
palindromic repeat (CRISPR)/Cas9, has made great progress in the field of gene function …

CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer

SC Selvakumar, KA Preethi, K Ross, D Tusubira… - Molecular Cancer, 2022 - Springer
Background Cancer is caused by a combination of genetic and epigenetic abnormalities.
Current cancer therapies are limited due to the complexity of their mechanism, underlining …

A novel anti-cancer therapy: CRISPR/Cas9 gene editing

XZ Chen, R Guo, C Zhao, J Xu, H Song, H Yu… - Frontiers in …, 2022 - frontiersin.org
Cancer becomes one of the main causes of human deaths in the world due to the high
incidence and mortality rate and produces serious economic burdens. With more and more …

[HTML][HTML] New advances in targeted gastric cancer treatment

DC Lazăr, S Tăban, M Cornianu, A Faur… - World journal of …, 2016 - ncbi.nlm.nih.gov
Despite a decrease in incidence over past decades, gastric cancer remains a major global
health problem. In the more recent period, survival has shown only minor improvement …

[HTML][HTML] Precision medicine in gastric cancer

P Bonelli, A Borrelli, FM Tuccillo… - World journal of …, 2019 - ncbi.nlm.nih.gov
Gastric cancer (GC) is a complex disease linked to a series of environmental factors and
unhealthy lifestyle habits, and especially to genetic alterations. GC represents the second …

Targeting gastric cancer stem cells to enhance treatment response

X Rao, C Zhang, H Luo, J Zhang, Z Zhuang, Z Liang… - Cells, 2022 - mdpi.com
Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

A review on CRISPR/Cas: a versatile tool for cancer screening, diagnosis, and clinic treatment

X Yang, B Zhang - Functional & Integrative Genomics, 2023 - Springer
Cancer is one of the leading causes of death worldwide and it has the trend of increase
incidence. However, in the past decades, as quickly developed new technologies and …

Medical management of gastric cancer: a 2017 update

N Charalampakis, P Economopoulou… - Cancer …, 2018 - Wiley Online Library
Gastric cancer remains a considerable health burden throughout the world. The Cancer
Genome Atlas (TCGA) analysis has recently unveiled 4 genotypes of gastric cancer with …

Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer

H Zhang, C Qin, C An, X Zheng, S Wen, W Chen, X Liu… - Molecular cancer, 2021 - Springer
Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …