Malaria-associated acute kidney injury in African children: prevalence, pathophysiology, impact, and management challenges

A Batte, Z Berrens, K Murphy, I Mufumba… - … of Nephrology and …, 2021 - Taylor & Francis
Acute kidney injury (AKI) is emerging as a complication of increasing clinical importance
associated with substantial morbidity and mortality in African children with severe malaria …

Acute kidney injury is associated with impaired cognition and chronic kidney disease in a prospective cohort of children with severe malaria

AL Conroy, RO Opoka, P Bangirana, R Idro… - BMC medicine, 2019 - Springer
Background Acute kidney injury (AKI) is a recognized complication of pediatric severe
malaria, but its long-term consequences are unknown. Methods Ugandan children with …

Acute kidney injury is common in pediatric severe malaria and is associated with increased mortality

AL Conroy, M Hawkes, RE Elphinstone… - Open forum …, 2016 - academic.oup.com
Background. Acute kidney injury (AKI) is a well recognized complication of severe malaria in
adults, but the incidence and clinical importance of AKI in pediatric severe malaria (SM) is …

Acute kidney injury, persistent kidney disease, and post-discharge morbidity and mortality in severe malaria in children: a prospective cohort study

R Namazzi, A Batte, RO Opoka, P Bangirana… - …, 2022 - thelancet.com
Background Globally, 85% of acute kidney injury (AKI) cases occur in low-and-middle-
income countries. There is limited information on persistent kidney disease (acute kidney …

Acute kidney injury interacts with coma, acidosis, and impaired perfusion to significantly increase risk of death in children with severe malaria

R Namazzi, R Opoka, D Datta… - Clinical Infectious …, 2022 - academic.oup.com
Background Mortality in severe malaria remains high in children treated with intravenous
artesunate. Acute kidney injury (AKI) is a common complication of severe malaria, but the …

Malaria and acute kidney injury

DD Brown, S Solomon, D Lerner, M Del Rio - Pediatric Nephrology, 2020 - Springer
Malaria is a parasitic infection transmitted by mosquitos, resulting in significant morbidity and
mortality. It affects 212 million worldwide, causing death in up to 303,000 children annually …

Acute kidney injury in Ugandan children with severe malaria is associated with long-term behavioral problems

MR Hickson, AL Conroy, P Bangirana, RO Opoka… - PLoS …, 2019 - journals.plos.org
Background Acute kidney injury (AKI) is a risk factor for neurocognitive impairment in severe
malaria (SM), but the impact of AKI on long-term behavioral outcomes following SM is …

Pathophysiology of acute kidney injury in malaria and non-malarial febrile illness: a prospective cohort study

MT Hawkes, A Leligdowicz, A Batte, G Situma, K Zhong… - Pathogens, 2022 - mdpi.com
Acute kidney injury (AKI) is a life-threatening complication. Malaria and sepsis are leading
causes of AKI in low-and-middle-income countries, but its etiology and pathogenesis are …

Malarial acute kidney injury in a paediatric intensive care unit

K Kapoor, S Gupta - Tropical doctor, 2012 - journals.sagepub.com
Acute kidney injury (AKI) is a serious complication of malaria which has a very high mortality
rate. A retrospective analysis of medical record data of children treated for malarial AKI in a …

Malaria and acute kidney injury

SK Mishra, BS Das - Seminars in nephrology, 2008 - Elsevier
Malaria is a major public health problem in tropical countries. About 500 million people
suffer from malaria, leading to death in 1 to 3 million cases. Acute kidney injury (AKI) is one …