[PDF][PDF] The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling

KV Gromova, E Thies, PC Janiesch, FP Lützenkirchen… - Cell Reports, 2023 - cell.com
Homeostatic synaptic plasticity adjusts the strength of synapses to restrain neuronal activity
within a physiological range. Postsynaptic guanylate kinase-associated protein (GKAP) …

KIF13A drives AMPA receptor synaptic delivery for long-term potentiation via endosomal remodeling

Y Gutiérrez, S López-García, A Lario… - Journal of Cell …, 2021 - rupress.org
The regulated trafficking of AMPA-type glutamate receptors (AMPARs) from dendritic
compartments to the synaptic membrane in response to neuronal activity is a core …

[PDF][PDF] The kinesin KIF21B regulates microtubule dynamics and is essential for neuronal morphology, synapse function, and learning and memory

M Muhia, E Thies, D Labonté, AE Ghiretti, KV Gromova… - Cell reports, 2016 - cell.com
The kinesin KIF21B is implicated in several human neurological disorders, including
delayed cognitive development, yet it remains unclear how KIF21B dysfunction may …

[HTML][HTML] Kinesin family of proteins Kif11 and Kif21B act as inhibitory constraints of excitatory synaptic transmission through distinct mechanisms

S Swarnkar, Y Avchalumov, BL Raveendra… - Scientific Reports, 2018 - nature.com
Despite our understanding of the functions of the kinesin family of motor proteins (Kifs) in
neurons, their specific roles in neuronal communication are less understood. To address …

[PDF][PDF] The atypical kinesin KIF26A facilitates termination of nociceptive responses by sequestering focal adhesion kinase

L Wang, Y Tanaka, D Wang, M Morikawa, R Zhou… - Cell reports, 2018 - cell.com
Kinesin superfamily proteins (KIFs) are molecular motors that typically alter the subcellular
localization of their cargos. However, the atypical kinesin KIF26A does not serve as a motor …

[HTML][HTML] The KIF1A homolog Unc-104 is important for spontaneous release, postsynaptic density maturation and perisynaptic scaffold organization

YV Zhang, SB Hannan, JV Kern, DT Stanchev, B Koç… - Scientific reports, 2017 - nature.com
The kinesin-3 family member KIF1A has been shown to be important for experience
dependent neuroplasticity. In Drosophila, amorphic mutations in the KIF1A homolog unc …

[HTML][HTML] Kif13b regulates PNS and CNS myelination through the Dlg1 scaffold

R Noseda, M Guerrero-Valero, V Alberizzi… - PLoS …, 2016 - journals.plos.org
Microtubule-based kinesin motors have many cellular functions, including the transport of a
variety of cargos. However, unconventional roles have recently emerged, and kinesins have …

[HTML][HTML] Polyglutamylation of tubulin's C-terminal tail controls pausing and motility of kinesin-3 family member KIF1A

DV Lessard, OJ Zinder, T Hotta, KJ Verhey… - Journal of Biological …, 2019 - ASBMB
The kinesin-3 family member KIF1A plays a critical role in site-specific neuronal cargo
delivery during axonal transport. KIF1A cargo is mislocalized in many neurodegenerative …

Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

J Zhao, AHK Fok, R Fan, PY Kwan, HL Chan, LHY Lo… - elife, 2020 - elifesciences.org
The kinesin I family of motor proteins are crucial for axonal transport, but their roles in
dendritic transport and postsynaptic function are not well-defined. Gene duplication and …

[PDF][PDF] The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A

L Huo, Y Yue, J Ren, J Yu, J Liu, Y Yu, F Ye, T Xu… - Structure, 2012 - cell.com
Kinesin-3 KIF1A plays prominent roles in axonal transport and synaptogenesis. KIF1A
adopts a monomeric form in vitro but acts as a processive dimer in vivo. The mechanism …