Recent studies have demonstrated that culture under hypoxia has beneficial effects on
mesenchymal stem cells (MSCs). However, there are limitations to achieving a stable …

Background Human dental pulp stem cell (DPSC)-mediated regenerative endodontics is a
promising therapy for damaged teeth; however, the hypoxic environment in root canals can …

As previously described by several authors, dental pulp stem cells (DPSCs), when
adequately stimulated, may acquire a neuronal-like phenotype acting as a favorable source …

Background Dental pulp stem cells (DPSCs) have been developed as a potential source of
mesenchymal stem cells (MSCs) for regeneration of dental pulp and other tissues. However …

The culture of cells under hypoxia is considered one of the hot topics of tissue engineering,
especially when exploring the proliferation capacity, a critical step for cellular-based …

Human dental pulp harbours unique stem cell population exhibiting mesenchymal
stem/stromal cell (MSC) characteristics. This study aimed to analyse the differentiation …

There is substantial evidence supporting the anti-inflammatory and regenerative potential of
dental pulp stem cells (DPSCs) through direct cell transplantation or paracrine action …

Atmospheric (in vitro) oxygen pressure is around 150 mm Hg (20% O 2), whereas
physiologic (in vivo) oxygen pressure ranges between 5 and 50 mm Hg (0.7–7% O 2). The …

Introduction. Stem cells are regularly cultured under normoxic conditions. However, the
physiological oxygen tension in the stem cell niche is known to be as low as 1‐2% oxygen …

Pulp regeneration has recently attracted interest in modern dentistry. However, the success
ratio of pulp regeneration is low due to the compromising potential of stem cells, such as …