Mechanisms of ischemic stroke in young adults are poorly understood. The aim of the study
was to investigate and compare the frequency of common variations in prothrombotic genes …

Objectives–To test the hypothesis whether risk genotypes of the prothrombotic gene
polymorphisms (I/D 4G5G PAI‐1, G1691A factor V point mutation, factor VII Arg/Gln353) are …

Genetic factors are involved in the individual predisposition to develop ischemic stroke (IS).
In the present study we tested the role of the Factor VII G10976A and–C122T …

Background and purpose The classical risk factors did not explain all the possible etiology of
cerebral stroke. Genetic polymorphisms responsible for thrombophilia were implicated …

Objectives: To investigate the relationship between an insertion/deletion (4G/5G)
polymorphism of the plasminogen activator inhibitor (PAI)‐1 gene and childhood patients …

Background and objectives: ischemic stroke (IS) is among the most frequent causes of death
worldwide; thus, it is of paramount relevance to know predisposing factors that may help to …

Background In young individuals, a genetically predisposing hypercoagulability and classic
modifying risk factors can act synergistically on the ischemic stroke risk development. The …

Background–Plasminogen activator inhibitor type 1 (PAI‐1) is the major inhibitor of
fibrinolysis. It was reported that PAI‐1 gene polymorphisms affected PAI‐1 level and might …

Background and Purpose—Impaired fibrinolytic function secondary to elevated plasminogen
activator inhibitor-1 (PAI-1) levels has been implicated in ischemic stroke. PAI-1 levels are …

The role of genetic risk factors for ischemic stroke seems to be in particular significance in
pediatric patients. Numerous polymorphic variants of genes encoding proteins, that is …