NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina

I Palazzo, K Deistler, TV Hoang, S Blackshaw… - …, 2020 - journals.biologists.com
Retinal regeneration is robust in some cold-blooded vertebrates, but this process is
ineffective in warm-blooded vertebrates. Understanding the mechanisms that suppress the …

Heparin-binding epidermal growth factor and fibroblast growth factor 2 rescue Müller glia-derived progenitor cell formation in microglia-and macrophage-ablated chick …

HM El-Hodiri, JR Bentley, AG Reske… - …, 2023 - journals.biologists.com
Recent studies have demonstrated the impact of pro-inflammatory signaling and reactive
microglia/macrophages on the formation of Müller glial-derived progenitor cells (MGPCs) in …

Jak/Stat signaling regulates the proliferation and neurogenic potential of Müller glia-derived progenitor cells in the avian retina

L Todd, N Squires, L Suarez, AJ Fischer - Scientific Reports, 2016 - nature.com
Müller glia are capable of de-differentiating and proliferating to become Müller glia-derived
progenitor cells (MGPCs) with the ability to regenerate retinal neurons. One of the cell …

Inflammation regulates the multi-step process of retinal regeneration in zebrafish

M Nagashima, PF Hitchcock - Cells, 2021 - mdpi.com
The ability to regenerate tissues varies between species and between tissues within a
species. Mammals have a limited ability to regenerate tissues, whereas zebrafish possess …

Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina

I Palazzo, L Kelly, L Koenig, AJ Fischer - Experimental neurology, 2023 - Elsevier
Müller glia are a cellular source for neuronal regeneration in vertebrate retinas. However,
the capacity for retinal regeneration varies widely across species. Understanding the …

BMP‐and TGFβ‐signaling regulate the formation of Müller glia‐derived progenitor cells in the avian retina

L Todd, I Palazzo, N Squires, N Mendonca, AJ Fischer - Glia, 2017 - Wiley Online Library
Müller glia‐derived progenitor cells (MGPCs) have the capability to regenerate neurons in
the retinas of different vertebrate orders. The formation of MGPCs is regulated by a network …

Retinoic acid-signaling regulates the proliferative and neurogenic capacity of Müller glia-derived progenitor cells in the avian retina

L Todd, L Suarez, C Quinn, AJ Fischer - Stem Cells, 2018 - academic.oup.com
In the retina, Müller glia have the potential to become progenitor cells with the ability to
proliferate and regenerate neurons. However, the ability of Müller glia-derived progenitor …

[HTML][HTML] Rapid, dynamic activation of Müller glial stem cell responses in zebrafish

CJ Sifuentes, JW Kim, A Swaroop… - … & visual science, 2016 - jov.arvojournals.org
Purpose: Zebrafish neurons regenerate from Müller glia following retinal lesions. Genes and
signaling pathways important for retinal regeneration in zebrafish have been described, but …

Mitogen‐activated protein kinase‐signaling stimulates Müller glia to proliferate in acutely damaged chicken retina

AJ Fischer, MA Scott, W Tuten - Glia, 2009 - Wiley Online Library
ABSTRACT Müller glia in the mature retina have the capacity to become progenitor-like cells
in a many different vertebrate classes. The cell-signaling pathways that control the ability of …

A comparative analysis of Müller glia-mediated regeneration in the vertebrate retina

D Gallina, L Todd, AJ Fischer - Experimental eye research, 2014 - Elsevier
This article reviews the current state of knowledge regarding the potential of Müller glia to
become neuronal progenitor cells in the avian retina. We compare and contrast the …