Heart disease is a major cause of death worldwide with increasing prevalence, which urges
the development of new therapeutic strategies. Over the last few decades, numerous small …

Heart failure (HF) is one of the major health and economic burdens worldwide, and its
prevalence is continuously increasing. The study of HF requires reliable animal models to …

The study of heart failure requires viable animal models whereby chronic changes in
myocardial structure and function can evolve and the progression of heart failure and left …

Preclinical large animal models of heart failure (HF) play a critical and expanding role in
translating basic science findings to the development and clinical approval of novel …

Congestive heart failure (HF) is a clinical syndrome, with hallmarks of fatigue and dyspnea,
that continues to be highly prevalent and morbid. Because of the growing burden of HF as …

Heart failure (HF) is a leading cause of morbidity and mortality in the United States. Despite
a number of important therapeutic advances for the treatment of symptomatic HF, 1 the …

Heart failure (HF) describes a heterogenous complex spectrum of pathological conditions
that results in structural and functional remodeling leading to subsequent impairment of …

Heart failure is a common, complex condition with a poor prognosis and increasing
incidence. The syndrome of heart failure comprises changes in electrophysiology …

Heart failure (HF) is a chronic, complex condition with increasing incidence worldwide,
necessitating the development of novel therapeutic strategies. This has led to the current …

Heart failure, a complex disorder with heterogeneous aetiologies remains one of the most
threatening diseases known. It is a clinical syndrome attributable to a multitude of factors that …