[HTML][HTML] Acetogenins-Rich Fractions of Annona coriacea Suppress Human Glioblastoma Viability and Migration by Regulating Necroptosis and MMP-2 Activity In Vitro
LR Sousa, AGS Oliveira, A Arantes, JGM Junqueira… - Molecules, 2023 - mdpi.com
Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis. Resection,
radiation therapy, and temozolomide (TMZ) are insufficient to increase survival, making the …
radiation therapy, and temozolomide (TMZ) are insufficient to increase survival, making the …
[HTML][HTML] Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells
AB Justino, RM Florentino, A França, ACML Filho… - PLoS …, 2021 - journals.plos.org
Plant species from Annonaceae are commonly used in traditional medicine to treat various
cancer types. This study aimed to investigate the antiproliferative potential of an alkaloid and …
cancer types. This study aimed to investigate the antiproliferative potential of an alkaloid and …
[HTML][HTML] Annona coriacea Mart. Fractions Promote Cell Cycle Arrest and Inhibit Autophagic Flux in Human Cervical Cancer Cell Lines
INF Gomes, RJ Silva-Oliveira, VA Oliveira Silva… - Molecules, 2019 - mdpi.com
Plant-based compounds are an option to explore and perhaps overcome the limitations of
current antitumor treatments. Annona coriacea Mart. is a plant with a broad spectrum of …
current antitumor treatments. Annona coriacea Mart. is a plant with a broad spectrum of …
[HTML][HTML] Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells
Annona cherimola Mill is a large green fruit with black seeds widely known to possess toxic
properties due to the presence of Annonaceous acetogenins. The present study investigates …
properties due to the presence of Annonaceous acetogenins. The present study investigates …
[PDF][PDF] Artabotryside A, a constituent from Descurainia sophia (L.) induces cell death in U87 glioma cells through apoptosis and cell cycle arrest at G2/M phase
Descurainia sophia (L.) commonly known as Webb ex Prantl (flixweed) is a Chinese
traditional medicinal plant. Seeds of flixweed are used in the treatment of some cancers …
traditional medicinal plant. Seeds of flixweed are used in the treatment of some cancers …
Annona muricata leaves induce G1 cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells
SZ Moghadamtousi, H Karimian, E Rouhollahi… - Journal of …, 2014 - Elsevier
Ethnopharmacological relevance Annona muricata known as “the cancer killer” has been
widely used in the traditional medicine for the treatment of cancer and tumors. The purpose …
widely used in the traditional medicine for the treatment of cancer and tumors. The purpose …
[HTML][HTML] The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of …
S Zorofchian Moghadamtousi, E Rouhollahi… - PloS one, 2015 - journals.plos.org
Annona muricata has been used in folk medicine for the treatment of cancer and tumors.
This study evaluated the chemopreventive properties of an ethyl acetate extract of A …
This study evaluated the chemopreventive properties of an ethyl acetate extract of A …
Cytotoxic effect of Annona muricata Linn leaves extract on Capan-1 cells
Annona muricata Linn has been reported to contain valuable bioactive compounds known
as Annonaceous acetogenins. These long chain fatty acids were widely discussed for its …
as Annonaceous acetogenins. These long chain fatty acids were widely discussed for its …
[HTML][HTML] The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines
Abstract Background The edible fruit Annona cherimola has previously shown many
nutritional and medicinal properties. The current study evaluates the anti-cancer and anti …
nutritional and medicinal properties. The current study evaluates the anti-cancer and anti …
Acetogenins from Annonaceae plants: Potent antitumor and neurotoxic compounds
NN das Chagas Lima, DC Faustino, KJ Allahdadi… - PharmaNutrition, 2022 - Elsevier
Background Acetogenins are compounds found in Annonaceae, such as soursop (A.
muricata) and pine cone (A. squamosa), and present cytotoxic properties, with …
muricata) and pine cone (A. squamosa), and present cytotoxic properties, with …