Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms
involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized …

Increased levels of acute‐phase reactants and lymphopenia are predictors of disease
severity in coronavirus disease 2019 (COVID‐19). This study aimed to investigate the role of …

Cell death mechanisms are crucial to maintain an appropriate environment for the
functionality of healthy cells. However, during viral infections, dysregulation of these …

SARS-CoV-2 induced marked lymphopenia in severe patients with COVID-19. However,
whether lymphocytes are targets of viral infection is yet to be determined, although SARS …

Rationale: Lymphopenia is common in severe coronavirus disease (COVID-19), yet the
immune mechanisms are poorly understood. As inflammatory cytokines are increased in …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …

A low count of CD4+ and CD8+ lymphocytes is a hallmark laboratory finding in the
coronavirus disease 2019 (COVID‐19). Using flow cytometry, we observed significantly …

Background COVID‐19 can present with lymphopenia and extraordinary complex
multiorgan pathologies that can trigger long‐term sequela. Aims Given that inflammasome …

Since the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), more than 6 million cases are confirmed …

Although SARS-CoV-2 severe infection is associated with a hyperinflammatory state,
lymphopenia is an immunological hallmark, and correlates with poor prognosis in COVID …