Background: In recent years, many novel alkaloids with anticancer activity have been found
in China, and some of them are promising for developing as anticancer agents. Objective …

Backgroud: Protein kinases play an important role in cell proliferation, differentiation,
mobility and cell cycle arrest etc. These enzymes act as important targets in developing …

Cancer is a frightful disease that still poses a'nightmare'worldwide, causing millions of
casualties annually imposing one of the human race's greatest health-care challenges that …

Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …

Cancer is characterized as the second leading cause of death worldwide despite several
therapies. In this regard, numerous researchers around the world are working on synthetic …

Considered as the second deadliest disease globally, cancer has captured the attention of
researchers who have been trying with perseverance to decode its hidden aspects, to find …

Tricyclic alkaloid-like compounds were synthesised in a few steps, via the bridging Ritter
reaction. The compounds were evaluated for their antiproliferative activity against the MCF-7 …

All types of cancers involve malfunction of genes that control cell growth and characterized
by uncontrolled growth and spread of abnormal cells. Among them, only about 5% of all …

Throughout history, naturally derived molecules have had countless applications in
medicine, pharmacy, and biology. This rich reservoir of natural compounds demonstrated …

Natural products have gained popularity worldwide for promoting healthcare, as well as
disease prevention. Alkaloids are important chemical compounds that serve as a rich …