Familial genetic and environmental risk profile and high blood pressure event: a prospective cohort of cardio-metabolic and genetic study

G Kolifarhood, MS Daneshpour, AS Zahedi… - Blood …, 2021 - Taylor & Francis
Background and aims High blood pressure is the heritable risk factor for cardiovascular
diseases. We investigated whether the presence of familial genetic and environmental risk …

Genetic predisposition to higher blood pressure increases risk of incident hypertension and cardiovascular diseases in Chinese

X Lu, J Huang, L Wang, S Chen, X Yang, J Li, J Cao… - …, 2015 - Am Heart Assoc
Although multiple genetic markers associated with blood pressure have been identified by
genome-wide association studies, their aggregate effect on risk of incident hypertension and …

Genetic predisposition to high blood pressure and lifestyle factors: associations with midlife blood pressure levels and cardiovascular events

R Pazoki, A Dehghan, E Evangelou, H Warren, H Gao… - Circulation, 2018 - Am Heart Assoc
Background: High blood pressure (BP) is a major risk factor for cardiovascular diseases
(CVDs), the leading cause of mortality worldwide. Both heritable and lifestyle risk factors …

A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32 669 individuals

AS Havulinna, J Kettunen, O Ukkola, C Osmond… - …, 2013 - Am Heart Assoc
Recent genome-wide association studies have identified genetic variants associated with
blood pressure (BP). We investigated whether genetic risk scores (GRSs) constructed of …

Gene–environment interactions related to blood pressure traits in two community‐based Korean cohorts

JE Lim, HO Kim, SY Rhee, MK Kim… - Genetic …, 2019 - Wiley Online Library
Hypertension is a complex disorder caused by genetic and environmental risk factors.
Recently, genome‐wide association studies (GWASs) identified more than 100 genetic …

Influence of blood pressure polygenic risk scores and environmental factors on coronary artery disease in the Korean Genome and Epidemiology Study

K Woo, JE Lim, EY Lee - Journal of Human Hypertension, 2024 - nature.com
The present study aimed to investigate the association of blood pressure polygenic risk
scores (BP PRSs) with coronary artery disease (CAD) in a Korean population and the …

Recent findings in the genetics of blood pressure and hypertension traits

N Franceschini, AP Reiner… - American journal of …, 2011 - academic.oup.com
We provide an overview of ongoing discovery efforts in the genetics of blood pressure (BP)
and hypertension (HTN) traits. Two large genome-wide association meta-analyses of …

Genes and family environment explain correlations between blood pressure and body mass index

J Cui, JL Hopper, SB Harrap - Hypertension, 2002 - Am Heart Assoc
The correlations between systolic blood pressure (SBP) and diastolic blood pressure (DBP),
and between SBP and body mass index (BMI), might result from genetic or environmental …

A review of the genetics of hypertension with a focus on gene-environment interactions

RJ Waken, L de Las Fuentes, DC Rao - Current hypertension reports, 2017 - Springer
Abstract Purpose of Review Here, we discuss the interpretation and modeling of gene-
environment interactions in hypertension-related phenotypes, with a focus on the necessary …

Genetic and environmental influences on blood pressure and body mass index in the national academy of sciences–national research council world war ii veteran …

B Wang, T Wu, MC Neale, R Verweij, G Liu, S Su… - …, 2020 - Am Heart Assoc
Blood pressure (BP) and obesity phenotypes may covary due to shared genetic or
environmental factors or both. Furthermore, it is possible that the heritability of BP differs …