Presynaptic plasticity is an activity-dependent change in the neurotransmitter release and
plays a key role in dynamic modulation of synaptic strength. Particularly, presynaptic …

Synaptic plasticity is a cellular model for learning and memory. However, the expression
mechanisms underlying presynaptic forms of plasticity are not well understood. Here, we …

Cyclic adenosine monophosphate (cAMP) is a crucial second messenger involved in both
pre-and postsynaptic plasticity in many neuronal types across species. In the hippocampal …

The cyclic adenosine monophosphate (cAMP)-dependent potentiation of neurotransmitter
release is important for higher brain functions such as learning and memory. To reveal the …

It is widely accepted that the hippocampus plays a major role in learning and memory. The
mossy fiber synapse between granule cells in the dentate gyrus and pyramidal neurons in …

Brain is continuously altered in response to experience and environmental changes. One of
the underlying mechanisms is synaptic plasticity, which is manifested by modification of …

The hippocampal mossy fiber (MF)–CA3 synapse exhibits NMDA receptor-independent long-
term potentiation (LTP), which is expressed by presynaptic mechanisms leading to …

Long‐term potentiation (LTP) at the hippocampal mossy fibre‐CA3 synapses can be
reversed (depotentiated) by long trains of low‐frequency stimulation (LFS). In the present …

The hippocampal mossy fiber synapse is a key synapse of the trisynaptic circuit. Post-tetanic
potentiation (PTP) is the most powerful form of plasticity at this synaptic connection. It is …

Understanding learning and memory mechanisms is an important goal in neuroscience. To
gain insights into the underlying cellular mechanisms for memory formation, synaptic …