[HTML][HTML] Extracellular vesicle-mediated targeting strategies for long-term health benefits in gestational diabetes

S Nair, V Ormazabal, F Carrion, A Handberg… - Clinical …, 2023 - portlandpress.com
Extracellular vesicles (EVs) are critical mediators of cell communication, playing important
roles in regulating molecular cross-talk between different metabolic tissues and influencing …

Extracellular vesicles—new players in cell-to-cell communication in gestational diabetes mellitus

C Palma, HD McIntyre, C Salomon - Biomedicines, 2022 - mdpi.com
Research in extracellular vesicles (EVs) has contributed to a better understanding of
physiological and pathophysiological conditions. Biologically active cargo, such as miRNAs …

Extracellular vesicles and their role in gestational diabetes mellitus

LB James-Allan, SU Devaskar - Placenta, 2021 - Elsevier
Gestational diabetes mellitus (GDM) is a complex disorder that is defined by glucose
intolerance with onset during pregnancy. The incidence of GDM is increasing worldwide …

Protein Profiling of Placental Extracellular Vesicles in Gestational Diabetes Mellitus

N Kandzija, S Payne, WR Cooke, F Seedat… - International Journal of …, 2024 - mdpi.com
Throughout pregnancy, some degree of insulin resistance is necessary to divert glucose
towards the developing foetus. In gestational diabetes mellitus (GDM), insulin resistance is …

Extracellular vesicles are dynamic regulators of maternal glucose homeostasis during pregnancy

HC Zierden, R Marx-Rattner, KD Rock… - Scientific reports, 2023 - nature.com
Homeostatic regulation of the maternal milieu during pregnancy is critical for maternal and
fetal health. The placenta facilitates critical communication between maternal and fetal …

Placenta-derived exosomes and gestational diabetes mellitus

X Liu, H Qiu - Diabetes, Metabolic Syndrome and Obesity: Targets …, 2022 - Taylor & Francis
Gestational diabetes mellitus (GDM) refers to different degrees of glucose metabolism
abnormalities that occur or be first discovered during pregnancy. It is closely related to many …

Extracellular vesicles as critical mediators of maternal-fetal communication during pregnancy and their potential role in maternal metabolism

S Nair, C Salomon - Placenta, 2020 - Elsevier
Extracellular vesicles (EVs) have been implicated in the pathophysiology of metabolic
disorders by transferring biologically active molecules such as miRNAs and proteins to …

Extracellular vesicles and their potential role inducing changes in maternal insulin sensitivity during gestational diabetes mellitus

S Nair, V Ormazabal, M Lappas… - American Journal of …, 2021 - Wiley Online Library
Gestational diabetes mellitus (GDM) is one of the most common endocrine disorders during
gestation and affects around 15% of all pregnancies worldwide, paralleling the global …

Advances in extracellular vesicles as mediators of cell-to-cell communication in pregnancy

S Nair, M Razo-Azamar, N Jayabalan… - Cytokine & Growth …, 2023 - Elsevier
Cell-to-cell communication mediated by Extracellular Vesicles (EVs) is a novel and
emerging area of research, especially during pregnancy, in which placenta derived EVs can …

Extracellular vesicles as markers and mediators of pregnancy complications: gestational diabetes, pre‐eclampsia, preterm birth and fetal growth restriction

R Farrelly, MG Kennedy, R Spencer… - The Journal of …, 2023 - Wiley Online Library
In high income countries, approximately 10% of pregnancies are complicated by pre‐
eclampsia (PE), preterm birth (PTB), fetal growth restriction (FGR) and/or macrosomia …