The myostatin (MSTN) gene is important because of its role in regulation of skeletal muscle
growth in all vertebrates. In this study, CRISPR/Cas9 was utilized to successfully target the …

Genome editing is a powerful tool as a new breeding technology including for aquaculture
because of the high efficiency of gene targeting without the requirement for exogenous gene …

Channel catfish, Ictalurus punctatus, is the most produced aquaculture species in the United
States, although production levels have decreased since their peak in 2003. Myostatin …

Myostatin (MSTN) suppresses skeletal muscle development and growth in mammals, but its
role in fish is less well understood. Here we used CRISPR/Cas9 to mutate the MSTN gene in …

Myostatin (mstn) belongs to the TGF-β family, which is mainly involved in the negative
regulation of myogenesis in vertebrates. Upon implementation of several gene-editing …

Myostatin (MSTN), a negative regulator of skeletal muscle development, is the major gene of
interest for improving animal breeding productivity, including for aquaculture. We introduced …

We have reported the production of myostatin (Pm-mstn) complete knockout red sea bream
(Pagrus major) using CRISPR/Cas9, and the Pm-mstn mutant exhibited a 17% increase in …

Yellow catfish (Pelteobagrus fulvidraco) is one of the most important freshwater aquaculture
species in China. However, its small size and lower meat yield limit its edible value …

Muscle growth and development are important aspects of chicken meat production, but the
underlying regulatory mechanisms remain unclear and need further exploration. CRISPR …

CRISPR/Cas9 has been widely used in generating site-specific genetically modified animal
models. Myostatin (MSTN) is a negative regulator of muscle mass, related to muscle growth …