Girls with either hypo-or hypergonadotropic hypogonadism need treatment with estrogens to
initiate puberty and maintain a normal hormonal milieu. The focus of this review is hormone …

Objective To characterize hormone replacement therapy in a cohort of adolescent males
and females with hypo-gonadotropic hypogonadism (HH) with a focus on changes in …

Background: Management of puberty in the hypogonadal girl remains controversial.
Estrogens have profound effects on growth and development. Oral estrogens, the most …

HRT is needed by many adolescents for varied reasons, all with hypogonadism as a
common endpoint. Despite the large numbers of patients for whom HRT is prescribed, little …

Abstract Study Objective To evaluate uterine development with estrogen replacement
therapy in patients with primary amenorrhea due to hypogonadism. Design and Setting …

Since the 1960s, oestrogen deficiency in hypogonadism in girls has been successfully
treated by a sort of analogous application of the menopausal hormone replacement therapy …

The overall goal of pubertal sex hormone replacement therapy (HRT) in girls is not only
about development of secondary sexual characteristics, but also to establish an adult …

Introduction Hormone replacement in females with hypogonadism is advocated to address
the various clinical aspects of estrogen deficiency. Areas covered This article focuses on …

Over the past 20 years, a clear secular trend toward the earlier onset of puberty has been
described. A better knowledge should help clinicians attempting to define both precocious …

Pubertal induction and hormone replacement therapy (HRT) during adolescence are
conducted with the aim of closely mirroring the pubertal changes that occur in children with a …