Aim This systematic literature review focused on identifying and describing paediatric
PROMs that incorporate pictorial approaches, providing children with more effective means …

Abstract Background and Aims Patient-reported outcome measures (PROMs) for children
(aged≤ 18 years) present methodological challenges. PROMs can be categorised by their …

Background Recent systematic reviews show varying methods for eliciting, modelling, and
reporting preference-based values for child health-related quality-of-life (HRQoL) outcomes …

Objective The aim of this study was to examine the level of agreement between self-and
proxy-reporting of health-related quality of life (HRQoL) in children (under 18 years of age) …

The US FDA and the European Medicines Agency (EMA) have issued incentives and laws
mandating clinical research in pediatrics. While guidances for the development and …

The value of a universal outcome measure such as the quality-adjusted life-year (QALY) has
long been recognized for health funding allocation decisions that span diverse patient …

Objective The aim of this study was to compare the psychometric performance of common
generic paediatric health-related quality-of-life instrument descriptive systems (PedsQL …

Abstract Background The Paediatric Quality of Life Inventory (PedsQL™) questionnaire is a
widely used, generic instrument designed for measuring health-related quality of life …

The pre-Socratic Greek philosopher Protagoras (490 BC–420 BC) made an argument about
2,500 years ago: Man is the measure of all things—of things which are, how they are, and of …

Although numerous paediatric-based health-related quality-of-life (HR-QOL) instruments are
currently in use, there still remain conceptual, methodological and developmental issues to …