A reproducible model of left ventricular failure in the closed-chest, anesthetized dog Page 1 A
reproducible model of left ventricular failure in the closed-chest, anesthetized dog L. Von Koch …

METHOD Dogs of 4.8 to 15.4 kilograms weight were used. Following anesthesia with
sodium pentobarbital, artificial respiration was applied through a tracheal cannula. The …

METHODS The following experiments were conducted in 22 open-chest mongrel dogs
weighing from 9 to 15Kg. Isometric systolic tension (IST) was measured prior to and 25-30 …

METHODS The experimental method described by Sarnoff and Berglund1 was modified to
permit its application with extracorporeal circulation. Healthy mongrel dogs weighing 11.5 to …

METHODS Thirty female mongrel dogs were anesthetized intravenously with sodium
pentobarbital(30 mg/kg). Under sterile conditions, a thoracotomy was performed and an …

A method for evaluating cardiac function in the intact animal over an extended period of time
based upon the ventricular response to graded proximal aortic obstruction has been …

A model of chronic cardiac failure has undergone extensive hemodynamic investigation.
Under anesthesia the homonymous and second diagonal coronary arteries of sheep have …

We describe a technique for the production of acute progressive right ventricular failure in
experimental animals that mimics the hemodynamic characteristics of right ventricular failure …

Materials and methods Mongrel dogs, weighing 14 to 28 kilograms, were anesthetized with
sodium pentobarbital (30 mg. per kilogram) and mechanically ventilated by 100 per cent …

Methods Thirty-four mongrel dogs, weighing 18 to 28 kilograms, were used. The animals
were anesthetized with pentobarbital sufficient to prevent skeletal muscle movement …