Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia–reperfusion-induced acute and chronic kidney injury

S Gatti, S Bruno, MC Deregibus, A Sordi… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. Several studies demonstrated that mesenchymal stem cells (MSCs) reverse
acute kidney injury (AKI) by a paracrine mechanism rather than by MSC transdifferentiation …

Mesenchymal stem cell-derived microvesicles protect against acute tubular injury

S Bruno, C Grange, MC Deregibus… - Journal of the …, 2009 - journals.lww.com
Administration of mesenchymal stem cells (MSCs) improves the recovery from acute kidney
injury (AKI). The mechanism may involve paracrine factors promoting proliferation of …

Bone marrow stem cells‐derived microvesicles protect against renal injury in the mouse remnant kidney model

J He, Y Wang, S Sun, M Yu, C Wang, X Pei, B Zhu… - …, 2012 - Wiley Online Library
Aims: Several studies have demonstrated administration of mesenchymal stem cells (MSC)
could reverse kidney injury by paracrine mechanisms rather than by MSC …

Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury

S Bruno, C Grange, F Collino, MC Deregibus… - PloS one, 2012 - journals.plos.org
Several studies demonstrated that treatment with mesenchymal stem cells (MSCs) reduces
cisplatin mortality in mice. Microvesicles (MVs) released from MSCs were previously shown …

Therapeutic potential of mesenchymal stem cell-derived microvesicles

L Biancone, S Bruno, MC Deregibus… - Nephrology Dialysis …, 2012 - academic.oup.com
Several studies have demonstrated that mesenchymal stem cells have the capacity to
reverse acute and chronic kidney injury in different experimental models by paracrine …

[HTML][HTML] Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of …

V Cantaluppi, S Gatti, D Medica, F Figliolini, S Bruno… - Kidney international, 2012 - Elsevier
Endothelial progenitor cells are known to reverse acute kidney injury by paracrine
mechanisms. We previously found that microvesicles released from these progenitor cells …

Mesenchymal stem cells, not conditioned medium, contribute to kidney repair after ischemia-reperfusion injury

L Xing, R Cui, L Peng, J Ma, X Chen, RJ Xie… - Stem cell research & …, 2014 - Springer
Introduction Studies have shown that stem cells exert their therapeutic effects on acute
kidney injury (AKI) through paracrine/endocrine actions. If the protective effect is mediated in …

Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury

F Togel, K Weiss, Y Yang, Z Hu… - American Journal …, 2007 - journals.physiology.org
Acute kidney injury (AKI) is a major clinical problem in which a critical vascular,
pathophysiological component is recognized. We demonstrated previously that …

Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury

HY Choi, SJ Moon, BB Ratliff, SH Ahn, A Jung, M Lee… - PloS one, 2014 - journals.plos.org
We recently demonstrated the use of in vitro expanded kidney-derived mesenchymal stem
cells (KMSC) protected peritubular capillary endothelial cells in acute renal ischemia …

Mesenchymal stem cells ameliorate tissue damages triggered by renal ischemia and reperfusion injury

P Semedo, PM Wang, TH Andreucci… - Transplantation …, 2007 - Elsevier
BACKGROUND: Ischemia and reperfusion injury (I/R) is the major cause of acute renal
failure (ARF) with high mortality rates. Because alternative therapies are needed, we …