Ethnic differences of breast cancer genomics have prompted us to investigate the spectra of
BRCA1 and BRCA2 mutations in different populations. The prevalence and effect of BRCA 1 …

Breast cancer is the most prevalent cancer in Asian females, and the incidence of breast
cancer has been increasing in Asia. Because Asian patients develop breast cancer at a …

Purpose Over the past three decades, the incidence rate of breast cancer (BC) among Arab
women has continually increased. However, data on the prevalence of BRCA1/2 mutations …

Background Germline mutations BRCA1 and BRCA2 contribute almost equally in the
causation of breast cancer (BC). The type of mutations in the Indian population that cause …

We determined the prevalence and characteristics of BRCA1/2 germline mutations in a large
cohort of Chinese women with breast cancer. A total of 5931 unselected Chinese women …

Abstract Background About 5–10% of incidences of breast cancers have been reported as a
result of germline mutations of BRCA genes. However, the mutational spectrum of BRCA1 …

Approximately 5%–10% of breast cancers are due to genetic predisposition caused by
germline mutations; the most commonly tested genes are BRCA1 and BRCA2 mutations …

Breast cancer (BC) is the most common cancer of women all over the world. BRCA1 and
BRCA2 gene mutations comprise the most important genetic susceptibility of BC. Except for …

Background Ethnic variations in breast cancer epidemiology and genetics have
necessitated investigation of the spectra of BRCA1 and BRCA2 mutations in different …

Background Breast cancer is the most common malignancy among women worldwide and
the leading cause of cancer death in economically developing countries. We sought to study …